Biological applications of high aspect ratio nanoparticles

Magnetic bead handling on-chip: new opportunities for analytical applications

“…The use of magnetic bead solutions for biomedical applications, but excluding microfluidic applications, has been reviewed several times Safarik and Safarikova 2002;Shinkai 2002;Pankhurst et al 2003;Bauer et al 2004). The fact that a magnetic field gradient can be used to either remotely position or selectively filter biological materials attached to a magnetic bead has led to a number of obvious applications.…”

Carbon Nanotubes – Imprinted Polymers: Hybrid Materials for Analytical Applications

“…In particular, extensive researches have been focused on medicine and biomedical engineering for the investigation of the interactions between nanomaterials and biological systems (Foldvari & Bagonluri, 2008;Desai, 2000). Potential products of bionanotechnology in the pharmaceutical and biomedical industry are refered as nanomedicines, including materials to be employed as clinical bio-analytical diagnostics Pantarotto et al, 2003), carriers to improve controlled and targeted drug release (Leary et al, 2006;Sinha & Yeow, 2005) and additives to improve solubility and bioavailability of poorly soluble drugs (Ajayan et al, 1993), novel tissue engineered scaffolds and devices (Bauer et al, 2004;Mazzola, 2003;Kikuchi et al, 2004).…”

Magnetic nanowires (Fe, Fe-Co, Fe-Ni) – magnetic moment reorientation in respect of wires composition

“…Nanostructures with a high aspect ratio and not uniform composition can be used for multiple biological sensing, biological separations, and gene delivery [3][4][5]. Nanowires saturation magnetization and coercive fi eld can be modifi ed by the combination of different elements in one superstructure [6]. Chemical surface modifi cation of magnetic wires can be tailored for selective interaction with molecules of special interest [7].…”

“…Wires fabrication method (electrodeposition) is very attractive in comparison to other methods because of its fl exibility to the size and shape of the template [8,9]. The element specifi c deposition processes were studied in case of thin fi lms while the nanowires deposition shows much complex behavior [6,10] and the mechanism of alloy nanowires deposition has not been investigated in detail so far.…”