Biological control of sheep nematode Haemonchus contortus using edible mushrooms

Comans-Pérez, Ricardo José; Sánchez, José E.; Al-Ani, Laith Khalil Tawfeeq; González-Cortazar, Manasés; Castañeda-Ramírez, Gloria Sarahi; Gives, Pedro Mendoza de; Sánchez-García, Alma Delia; Millán-Orozco, Jair; Aguilar-Marcelino, Liliana

doi:10.1016/j.biocontrol.2020.104420

Cited by 18 publications

(7 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The column was monitored by UV lamp (254 and 366 nm). Fractions of 35 mL were collected as follows: [(1-6), n-hexane-EtOAc (90:10)] [ (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24), n-hexane-EtOAc (8:2)], [ (25)(26)(27)(28)(29), n-hexane-EtOAc (7:3)], [ (30), n-hexane-EtOAc (6:4)], [ (31), n-hexane-EtOAc (1:1)], [ (32), n-hexane-EtOAc (4:6)], [ (33), n-hexane-EtOAc (3:7)], [ (34), n-hexane-EtOAc (2:8)] [ (35), n-hexane-EtOAc (1:9)], [(36), EtOAc-MeOH (9:1)] [(37), MeOH (100%)]. These fractions were pooled according to their TLC profiles into 10 subfractions F1 to F10 as follows: F1 (1-3; 0.05 g), F2 (4-7; 2.13 g), F3 (8-10; 0.24 g), F4 (11-13; 0.04 g), F5 (14-18; 0.04 g), F6 (19-23; 1.96 g), F7 (24-28; 0.39 g), F8 (29-31; 0.12 g), F9 (32-35; 0.06 g), and F10 (36-37; 0.39 g).…”

Section: Isolation Of Compounds 1 Andmentioning

confidence: 99%

“…Mushrooms have been used across the globe for their medicinal properties and they are sources of potent pharmaceuticals [16]. Edible mushrooms have shown anthelmintic activity against Haemonchus contortus, which is also known as the barber's pole worm, and is a very common parasite and one of the most pathogenic nematodes of ruminants [17]. Recently, a cyclodepsipeptide PF1022A, isolated from fungal culture Mycelia sterilia showed anthelmintic activity against Ascaridia galli in chickens [18].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: Natural Fungal Compounds and Synthetic Derivatives with In Vitro Anthelmintic Activities and Antiproliferative Effects against Two Human Cancer Cell Lines

et al. 2022

View full text Add to dashboard Cite

Neglected tropical diseases affect the world’s poorest populations with soil-transmitted helminthiasis and schistosomiasis being among the most prevalent ones. Mass drug administration is currently the most important control measure, but the use of the few available drugs is giving rise to increased resistance of the parasites to the drugs. Different approaches are needed to come up with new therapeutic agents against these helminths. Fungi are a source of secondary metabolites, but most fungi remain largely uninvestigated as anthelmintics. In this report, the anthelmintic activity of Albatrellus confluens against Caenorhabditis elegans was investigated using bio-assay guided isolation. Grifolin (1) and neogrifolin (2) were identified as responsible for the anthelmintic activity. Derivatives 4–6 were synthesized to investigate the effect of varying the prenyl chain length on anthelmintic activity. The isolated compounds 1 and 2 and synthetic derivatives 4–6, as well as their educts 7–10, were tested against Schistosoma mansoni (adult and newly transformed schistosomula), Strongyloides ratti, Heligmosomoides polygyrus, Necator americanus, and Ancylostoma ceylanicum. Prenyl-2-orcinol (4) and geranylgeranyl-2-orcinol (6) showed promising activity against newly transformed schistosomula. The compounds 1, 2, 4, 5, and 6 were also screened for antiproliferative or cytotoxic activity against two human cancer lines, viz. prostate adenocarcinoma cells (PC-3) and colorectal adenocarcinoma cells (HT-29). Compound 6 was determined to be the most effective against both cell lines with IC50 values of 16.1 µM in PC-3 prostate cells and 33.7 µM in HT-29 colorectal cells.

show abstract

Section: Isolation Of Compounds 1 Andmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: Natural Fungal Compounds and Synthetic Derivatives with In Vitro Anthelmintic Activities and Antiproliferative Effects against Two Human Cancer Cell Lines

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The biological activity of edible mushroom, especially Pleurotus spp. and their derivatives, have been explored as alternative methods for agricultural pests (Cedillo, 2016;Pineda-Alegría et al, 2017;Cruz-Arévalo et al, 2020;Comans-Pérez et al, 2021). In this search, it has been observed that the excessive use of chemical compounds has led to resistance of some pathogenic organisms (nematodes, bacteria and mites), contamination of the environment and the presence of hazardous residues in food for human consumption (RAPAM, 2017;Aguilar-Marcelino et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

In vitro evaluation of methanol extracts of edible fungi Pleurotus ostreatus and Lentinula edodes against Rhyssomatus nigerrimus Fahraeus

Castañeda-Ramírez,

López-Guillen,

Cruz-López

et al. 2023

Braz. J. Biol.

View full text Add to dashboard Cite

The study aimed to evaluate the insecticidal activity of extracts of edible mushrooms Pleurotus ostreatus and Lentinula edodes against Rhyssomatus nigerrimus. Methanol:water extracts (70:30) of P. ostreatus and L. edodes were made and evaluated in two in vitro tests (exposure and immersion toxic effect) against R. nigerrimus. Subsequently, the toxicity test of the extracts against Artemia salina was evaluated. These extracts were subjected to colorimetric tests and gas chromatography-mass spectrometry. The results showed a mortality effect against R. nigerrimus of 50% for the P. ostreatus 2 extracts at a concentration of 20% in the immersion test. Likewise, in the toxic effect test, 90% mortality was observed after five days of exposure to a concentration of 10%. On the other hand, for the toxicity test, the extract that showed the values with the highest mortality against A. salina was P. ostreatus, starting with 80% mortality at 100μg/mL. The functional groups present in the extracts were saponins, coumarins, and alkaloids. Furthermore, the presence of more than 7 compounds in the mushroom extracts evaluated is reported. This study demonstrates the insecticidal activity of P. ostreatus and L. edodes fungal extracts and indicates the importance of using different in vitro tests to elucidate the mechanism of action for future studies.

show abstract

“…In addition, many natural compounds and plant extracts are helpful in controlling plant diseases and pests (Al-Ani et al, 2012 ; Mohammed et al, 2012 , 2013 ; Adetunji et al, 2019 ; Garganese et al, 2019 ; Jatoi et al, 2020 ). NF are used in the control of parasitic nematodes as bionematicides by parasitism, and produce toxins to kill nematodes, as well as induce defense and resistance mechanisms in plants against parasite nematodes (Abd-Elgawad and Askary, 2018 ; Sarker et al, 2020 ; Comans-Pérez et al, 2021 ; Girardi et al, 2022 ). NF as biological control factors are the best method to use in sustainable agriculture.…”

Section: Introductionmentioning

confidence: 99%

Strategy of Nematophagous Fungi in Determining the Activity of Plant Parasitic Nematodes and Their Prospective Role in Sustainable Agriculture

Al-Ani

Soares

Sharma

et al. 2022

Front. Fungal Biol.

Self Cite

View full text Add to dashboard Cite

In this review, we supply a framework for the importance of nematophagous fungi (nematophagous fungi [NF]) and their role in agricultural ecosystems. We characterize the taxonomy, diversity, ecology, and type of NF, depending on their interaction with plant-parasitic nematodes (PPNs). We described potential mechanisms of NF in the control of PPNs, the efficiency and methods of utilization, and the use of nematicides in sustainable agriculture. We explain the utilization of NF in nanotechnology as a new approach. NF are significant in the soil for having the effective potential for use in sustainable agriculture. These types of fungi belong to wide taxa groups, such as Ascomycota, Basidiomycota, and other groups. Diverse NF are available in different kinds of soil, especially in soils that contain high densities of nematodes. There is a relationship between the environment of nematodes and NF. NF can be divided into two types according to the mechanisms that affect nematodes. These types are divided into direct or indirect effects. The direct effects include the following: ectoparasites, endoparasites, cyst, or egg parasites producing toxins, and attack tools as special devices. However, the indirect effect comprises two groups: paralyzing toxins and the effect on the life cycle of nematodes. We explained the molecular mechanisms for determining the suitable conditions in brief and clarified the potential for increasing the efficacy of NF to highly impact sustainable agriculture in two ways: directly and indirectly.

show abstract

Biological control of sheep nematode Haemonchus contortus using edible mushrooms

Cited by 18 publications

References 19 publications

Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: Natural Fungal Compounds and Synthetic Derivatives with In Vitro Anthelmintic Activities and Antiproliferative Effects against Two Human Cancer Cell Lines

Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: Natural Fungal Compounds and Synthetic Derivatives with In Vitro Anthelmintic Activities and Antiproliferative Effects against Two Human Cancer Cell Lines

In vitro evaluation of methanol extracts of edible fungi Pleurotus ostreatus and Lentinula edodes against Rhyssomatus nigerrimus Fahraeus

Strategy of Nematophagous Fungi in Determining the Activity of Plant Parasitic Nematodes and Their Prospective Role in Sustainable Agriculture

Contact Info

Product

Resources

About