Biological effects of resveratrol

Progress on Understanding the Anticancer Mechanisms of Medicinal Mushroom: Inonotus Obliquus

“…Among them, Bcl-2 can form ion channels in biological membranes, which then influence the permeability of intracellular membranes, and thus the mitochondrial contents released into the cytoplasm , potentially resulting in the activation of caspase-3 and thereby leading to the induction of apoptosis. However, the overexpression of Bcl-2 protein can rescue cells from apoptosis by maintaining membrane integrity and preventing the release of mitochondrial contents (Frémont, 2000). Bax is a pro-apoptotic factor that translocates from the cytosol to the outer mitochondrial membrane, where it forms heterodimers with Bcl-2 protein to create pores and mediate the release of cytochrome c (Park et al, 2007).…”

Effect of resveratrol on matrix metalloproteinase-2 (MMP-2) and Secreted Protein Acidic and Rich in Cysteine (SPARC) on human cultured glioblastoma cells

“…Resveratrol (trans-3,4′,5-trihydrostilbene) is a polyphenol found in various fruits and vegetables, and has many biological and pharmaceutical properties [19][20][21]. It is reported to be one of the most potent chemopreventive agents inhibiting cellular processes associated with tumor development, including initiation, promotion, and progression [22,23].…”

Synthesis and electrochemical study of new 3-(hydroxyphenyl)benzo[f]coumarins

“…Resveratrol, a 3,4',5-trihydroxystilbene, produced by some spermatophytes species, such as vines, in response to external damage, is a natural polyphenolic compound extensively studied [13] due to anti-inflammatory, antioxidant, cardio-protective (vasodilator and platelet anti-aggregator), anticancer and enzymatic inhibitory properties [14,15].…”