Biomagnetic localization of ventricular arrhythmias.

Moshage, Werner; Achenbach, S.; Göhl, K.; Weikl, A; Bachmann, K.; P, Wegener; Schneider, Simon; Härer, Wolfgang

doi:10.1148/radiology.180.3.1714612

Cited by 30 publications

(17 citation statements)

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“…The development of an amagnetic, MR-compatible pacing catheter permitted the exact verification of the localization accuracy of the combined method of multichannel magnetocardiography and MR imaging. Our investigations of paced and spontaneous arrhythmias could demonstrate that multichannel magnetocardiography constitutes a method that permits the non-invasive localization of arrhythmogenic tissues in the heart with an error of less than 10 mm [16][17].…”

Section: Discussionmentioning

confidence: 81%

Clinical magnetocardiography: Experience with a biomagnetic multichannel system

et al. 1991

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The magnetic fields caused by the human heart's electrical activity were coherently recorded with a biomagnetic multichannel system (KRENIKON) during 1 to 10 minutes in 49 patients. 31 to 37 magnetic channels were recorded simultaneously with the ECG and respiration. Comparison of a magnetic index and the Sokolow-Lyon index to echocardiographic findings in the quantification of left ventricular hypertrophy demonstrated the superiority of the magnetocardiogram (MCG) as compared to the ECG. The magnetocardiographic investigation of patients with WPW-Syndrome, ventricular extrasystoles, ventricular tachycardia, and paced ventricular beats demonstrated that multichannel magnetocardiography permits the non-invasive three dimensional localization of arrhythmogenic tissue with high spatial accuracy.

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Section: Discussionmentioning

confidence: 81%

Clinical magnetocardiography: Experience with a biomagnetic multichannel system

et al. 1991

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“…Non-invasive localization of cardiac arrhythmias, presently the most important application of magnetocardiography, has been reported before [6,8,[19][20][21]. for the current source and the volume conductor), individual patient positioning and the coordinate transfer between MCG and MR imaging.…”

Section: Discussionmentioning

confidence: 99%

“…However, it was not until the availability of multichannel SQUID systems installed in magnetically shielded rooms that the registration quality was sufficient for the development of clinical applications [7][8][9]. Making use of the available technology, we investigated the applicability and accuracy of multichannel magnetocardiographic recordings for non-invasive 3-dimensional localization in phantom and patient studies, by comparison to established reference methods, and, as a gold standard, by the confirmation of localization results through successful high frequency catheter ablation.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the non-invasive localization accuracy of cardiac arrhythmias attainable by multichannel magnetocardiography (MCG)

et al. 1996

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The accuracy of multichannel magnetocardiography (MCG) for the non-invasive localization of cardiac arrhythmias was investigated. A non-magnetic catheter was used in phantom studies and for cardiac pacing of 6 patients. In a clinical setting, 32 patients with WPW-syndrome, 37 patients with premature ventricular complexes and 12 patients with ventricular tachycardia were studied and the MCG results compared to reference methods, including invasive electrophysiological mapping. Phantom and pacing studies demonstrated the spatial localization accuracy to be better than 15 mm for a dipole-to-dewar distance below 15 cm. In all patients with structural cardiac disease, the ectopic focus was localized at the margin of the damaged area, serving as a proof of MCG localization. Invasive mapping confirmed the MCG result whenever performed (42 patients). In 11 patients (9 WPW, 2 VT) the MCG localization result was verified by successful HF catheter ablation as a gold standard. MCG permits the non-invasive localization of cardiac arrhythmias with high spatial accuracy. MCG guided HF catheter ablation constitutes a new concept of non-invasive localization and minimally invasive causal therapy.

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“…Likewise, the orientation of stimulated ectopic beats was calculated from the magnetic field distribution and verified by MRI. The authors concluded that multichannel magnetocardiographic studies enable the completely non-invasive localization of ventricular arrhythmias [61]. The results were obtained in parallel by other investigators [62].…”

Section: Rozkład Prądów Nasierdziowych U Pacjenta Z Ciasnym Zwężenimentioning

confidence: 74%

“…Pioneering work concerning the exactness of biomagnetic localization was done by Moshage et al [61]. The authors studied patients with ventricular arrhythmias by combining MCG data with magnetic resonance imaging (MRI).…”

Section: Rozkład Prądów Nasierdziowych U Pacjenta Z Ciasnym Zwężenimentioning

confidence: 99%

Special article Magnetocardiography in clinical cardiology. Status quo and future applications

Leithäuser¹,

Jung²,

Park³

2011

pwki

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215Magnetocardiography in clinical cardiology. Status quo and future applications Magnetokardiografia w kardiologii klinicznej. Stan obecny i przyszłe zastosowania B Bo or ri is s L Le ei it th hä äu us se er r 1 1 , , F Fr ri ie ed dr ri ic ch h J Ju un ng g 2 2 , , J Ja ai i--W Wu un n P Pa ar rk k Special article/Artykuł specjalny A b s t r a c tMagnetocardiography (MCG) is a non-contact, non-invasive technique for the assessment of electromagnetic activity of the human heart. Theoretical considerations and comparative studies indicate different information content between MCG and electrocardiography (ECG). Although many questions about cardiac pathophysiology and electrophysiology can be answered by MCG studies, measurement of biomagnetism is still only marginally recognized as a valuable tool. Although MCG instrumentation (SQUIDs, MSR) and operation (liquid helium) are expensive and not available at the bedside, the gain of information drawn from the cardiac magnetic field is worth the effort. The MCG has superior sensitivity for ischaemic myocardium both at rest and under stress. Therefore, it may change one's ideas of decision making about invasive procedures. Compared to scintigraphy, which is a cumbersome method with the need of radioactivity exposure to the patient, MCG is as easy as bicycle ergometry but with higher sensitivity. In terms of risk stratification for sudden cardiac death, it seems to be possible that MCG in the future will provide additional information as to which patient will not benefit from prophylactic defibrillator implantation. However, appropriate clinical studies are lacking. Most interestingly, MCG appears to be practical and informative in the diagnosis of cardiac arrhythmias, and has sufficient spatial accuracy necessary for clinical purposes. It seems realistic that MCG-based localization of arrhythmogenic spots may guide the operator's ablation catheter, e.g. in patients with relapsing AF after a first successful ablation procedure. There is enough room for fantasy which question in clinical cardiology remains to be answered by MCG. K Ke ey y w wo or rd ds s: : magnetocardiography, coronary heart disease, ischaemia, risk stratification, arrhythmia, atrial fibrillation S t r e s z c z e n i e Magnetokardiografia (ang. magnetocardiography, MCG) jest bezkontaktową, nieinwazyjną metodą pomiaru pola magnetycznego ludzkiego serca. Założenia teoretyczne oraz badania porównawcze wskazują, że MCG i EKG dostarczają odmiennych informacji. Pomiar pola magnetycznego jest nadal w niewielkim stopniu uważany za wartościowe narzędzie, pomimo że badania MCG mogą udzielić odpowiedzi na wiele pytań dotyczących patofizjologii serca i elektrofizjologii. Chociaż oprzyrządowanie konieczne do MCG (SQUIDs, MSR) i jego obsłu-ga (ciekły hel) są drogie i nie są dostępne jako badania przyłóżkowe, to informacja uzyskiwana z badań pola magnetycznego serca jest warta tych wysiłków. Magnetokardiografia charakteryzuje się większą czułością w wykrywaniu niedokrwienia miokardium zarówno w warunkach spoczynkow...

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Biomagnetic localization of ventricular arrhythmias.

Cited by 30 publications

References 0 publications

Clinical magnetocardiography: Experience with a biomagnetic multichannel system

Clinical magnetocardiography: Experience with a biomagnetic multichannel system

Evaluation of the non-invasive localization accuracy of cardiac arrhythmias attainable by multichannel magnetocardiography (MCG)

Special article Magnetocardiography in clinical cardiology. Status quo and future applications

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