Biomechanical parameter determination of scaffold-free cartilage constructs (SFCCs) with the hyperelastic material models Yeoh, Ogden and Demiray

Abstract

Abstract:The biomechanical properties are crucial indicators for the functional characterization of cartilaginous tissue. In this contribution native articular cartilage and three-dimensional sca old-free cartilage constructs (SFCCs) are characterized by hyperelastic material models (Yeoh, Ogden and Demiray). SFCCs were developed for the therapy of damaged articular cartilage. The normalized error (NE) of t and experiment is in the range of 0.04 and 0.13. The material model Yeoh with two parameters yields the best t. The stress-like parameter c is 0.489 MPa for native cartilage, 0.120 MPa and 0.041 MPa for SFCCs produced from mesenchymal stem cells and chondrocytes, respectively. The signi cance of the ts and the derived parameters are presented and evaluated.