Biomechanical properties of ascending aorta and pulmonary trunk in pigs and humans

Li, Wen-Chun; Yu, Miao; Zhang, Hongmei; Wang, Hanqin; Xi, Gao; Yao, Bo-Chun; Deng, Zhao-Hong; Zeng, Yanjun

doi:10.1111/j.1399-3089.2008.00498.x

Cited by 19 publications

(11 citation statements)

References 25 publications

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“…Although the mechanical properties of thoracic aortas of young pigs might not exactly match those of elderly people, it has been reported that there was no significant difference in the elastic modulus between the human and pig aorta. 10 Correlations between the ultimate stress and the tangent elastic modulus, and between the ultimate stress and the parameter s r obtained in this study were almost similar for human and porcine aortas (Fig. 8).…”

Section: Feasibility For Estimation Of Ultimate Stresssupporting

confidence: 71%

Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation

Sugita

Matsumotο

Ohashi

et al. 2011

Cardiovasc Eng Tech

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Rupture properties of thoracic aortic aneurysms (TAAs) were measured in vitro in a pressure-imposed test to predict the ultimate stress of TAAs from their mechanical behavior in a physiological pressure range. Each quadrilateral (ca. 20 9 20 mm 2 ) specimen of TAAs or porcine thoracic aortas (PTAs) was pressurized from the inner wall until rupture or up to 4500 mmHg, while its deformation was being monitored. In-plane stress r and strain e of the specimen were calculated using Laplace's law and deformations of the markers drawn on the specimen surface, respectively. Ultimate stress r max and tangent elastic modulus H were determined from the r-e curve as its maximum stress and slope, respectively. The tangent elastic modulus H of PTA specimens tended to increase with the increase in r, while that of TAA specimens tended to reach a plateau in a low-r region. This tendency was confirmed by fitting a function H = C r (1 À exp(Àr/s r )) to the HÀr relation of specimens: The yielding parameter s r was significantly lower in TAAs than PTAs. Furthermore, the logarithm of the parameter s r correlated significantly with r max , for all specimens. These results may indicate that s r is one of the candidate indices for rupture risk estimation.

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Section: Feasibility For Estimation Of Ultimate Stresssupporting

confidence: 71%

Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation

Sugita

Matsumotο

Ohashi

et al. 2011

Cardiovasc Eng Tech

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“…Second, careful manipulations of the vessel including: the release of the vessel from surrounding fascia and adipose tissue, inserting and firmly securing the catheter within the vessel for long-term lymph collection is critical for successful catheterization. Indeed, it is suggested that the structural integrity of the vessels in neonatal pigs is not as robust as in mature animals and as such can easily tear 39,40 . Using Q-tip applicators to slowly and gently separate fascial layers and fine blunt-ended instruments to pass the suture underneath the vessel greatly reduces the inadvertent puncture or tearing of the lymphatic vessel.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs

Uwiera

Mangat

Kelly

et al. 2016

JoVE

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Catheterization of the intestinal lymph trunk in neonatal pigs is a technique allowing for the long-term collection of large quantities of intestinal (central) efferent lymph. Importantly, the collection of central lymph from the intestine enables researchers to study both the mechanisms and lipid constitutes associated with lipid metabolism, intestinal inflammation and cancer metastasis, as well as cells involved in immune function and immunosurveillance. A ventral mid-line surgical approach permits excellent surgical exposure to the cranial abdomen and relatively easy access to the intestinal lymph trunk vessel that lies near the pancreas and the right ventral segment of the portal vein underneath the visceral aspect of the right liver lobe. The vessel is meticulously dissected and released from the surrounding fascia and then dilated with sutures allowing for insertion and subsequent securing of the catheter into the vessel. The catheter is exteriorized and approximately 1 L/24 hr of lymph is collected over a 7 day period. While this technique enables the collection of large quantities of central lymph over an extended period of time, the success depends on careful surgical dissection, tissue handling and close attention to proper surgical technique. This is particularly important with surgeries in young animals as the lymph vessels can easily tear, potentially leading to surgical and experimental failure. The video demonstrates an excellent surgical technique for the collection of intestinal lymph.

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“…Moreover, it has been found that pig blood vessels have similar behaviour to human blood vessels [24].…”

Section: Discussionmentioning

confidence: 99%

Measurement of Friction-induced Changes in Pig Aorta Fibre Organization by Non-invasive Imaging as a Model for Detecting the Tissue Response to Endovascular Catheters

et al. 2017

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Biomechanical properties of ascending aorta and pulmonary trunk in pigs and humans

Cited by 19 publications

References 25 publications

Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation

Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs

Measurement of Friction-induced Changes in Pig Aorta Fibre Organization by Non-invasive Imaging as a Model for Detecting the Tissue Response to Endovascular Catheters

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