Biomechanics

Fung, Y. C.

doi:10.1007/978-1-4757-2257-4

Cited by 1,999 publications

(153 citation statements)

References 270 publications

(390 reference statements)

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“…As shown in figures 3-6, the cervix, uterus and leiomyoma all have moduli that are directly proportional to frequency. It is tempting to compare these results using conventional viscoelastic models, such as those discussed in Fung (1993). However, several authors (Suki et al 1994, Taylor et al 2001, Nasseri and Bilston 2002, Chen et al 2003, Kiss et al 2004 have demonstrated that the conventional constitutive relations (i.e., Kelvin-Voigt model, the Maxwell model or the standard linear solid model) do not correctly or completely model the behaviour seen empirically, and the results are better correlated with some sort of power law.…”

Section: Discussionmentioning

confidence: 99%

“…Although there are more rigorous treatments in the literature (Christensen 1982, Fung 1993, the basic derivation is summarized here. When a viscoelastic material is deformed (i.e., strain is applied), it responds with some level of stress.…”

Section: Theorymentioning

confidence: 99%

“…The system was controlled using the ELF dynamic mechanical analysis (DMA) software, compressing the sample at a specified amplitude and frequency. For each amplitude range, the system was allowed to vibrate at the selected frequency for up to 10 s to allow the system to achieve equilibrium, to allow transients to decay and to allow the sample to precondition (Fung 1993). The time between acquiring data at any two frequencies was 5 s, at which point the sample was held at the mean strain level (1.5%, 2.5% and 3%, respectively).…”

Section: Methodsmentioning

confidence: 99%

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Frequency-dependent complex modulus of the uterus: preliminary results

et al. 2006

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The frequency-dependent complex moduli of human uterine tissue have been characterized. Quantification of the modulus is required for developing uterine ultrasound elastography as a viable imaging modality for diagnosing and monitoring causes for abnormal uterine bleeding and enlargement, as well assessing the integrity of uterine and cervical tissue. The complex modulus was measured in samples from hysterectomies of 24 patients ranging in age from 31 to 79 years. Measurements were done under small compressions of either 1 or 2%, at low pre-compression values (either 1 or 2%), and over a frequency range of 0.1-100 Hz. Modulus values of cervical tissue monotonically increased from approximately 30-90 kPa over the frequency range. Normal uterine tissue possessed modulus values over the same range, while leiomyomas, or uterine fibroids, exhibited values ranging from approximately 60-220 kPa.

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Section: Discussionmentioning

confidence: 99%

Section: Theorymentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Frequency-dependent complex modulus of the uterus: preliminary results

et al. 2006

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“…There is a strong link therefore between the mechanical and electrical properties of tissue during compression [25]. Biological tissue is typically described as a viscoelastic medium [35,36]. It follows that compressive BIS measurements should exhibit time-dependent behavior linked to the viscoelastic properties of the tissue in quantifying edema and edema changes during a dialysis session.…”

Section: Impedance Of Tofu Under Dynamic Loadingmentioning

confidence: 99%

“…This technique is commonly used to characterize the mechanical properties of viscoelastic materials. The stress and strain data were fit with a second order generalized Kelvin-Voigt model [36], a commonly used model to describe viscoelastic materials. Analytical expressions exist for both the stress-relaxation response (Eq.…”

Section: Impedance Of Tofu Under Dynamic Loadingmentioning

confidence: 99%

The feasibility of using compression bioimpedance measurements to quantify peripheral edema

Koziol

Pitre

Bull

et al. 2014

Journal of Electrical Bioimpedance

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The accurate assessment of body fluid volume is important in many clinical situations, especially in the determination of "dry weight" in a dialysis setting. Currently, no clinically applicable diagnostic system exists to determine the mechanical properties that accurately characterize peripheral edema in an objective and quantitative manner. We have developed a method for quantifying the impact of compression on the electrical properties of tissue by measuring stress-induced changes in bioimpedance (BIS). Using this method, we simultaneously measured the impedance and mechanical response of a tissue mimicking material (tofu) under both quasi-static and dynamic loading conditions. Our results demonstrate a temporal quantification of viscoelastic properties using a viscoelastic phantom tissue model.

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Viscoelastic properties of demineralized human dentin measured in water with atomic force microscope (AFM)-based indentation

Balooch

Wu-Magidi

Balazs

et al. 1998

J. Biomed. Mater. Res.

175

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Using an atomic force microscope (AFM) with an attachment specifically designed for indentation, we measured the mechanical properties of demineralized human dentin under three conditions: in water, in air after desiccation, and in water after rehydration. The static elastic modulus (E(h)r = 134 kPa) and viscoelastic responses (tau(epsilon) = 5.1 s and tau(sigma) = 6.6 s) of the hydrated, demineralized collagen scaffolding were determined from the standard linear solid model of viscoelasticity. No significant variation of these properties was observed with location. On desiccation, the samples showed considerably larger elastic moduli (2 GPa), and a hardness value of 0.2 GPa was measured. Upon rehydration the elastic modulus decreased but did not fully recover to the value prior to dehydration (381 kPa).

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Biomechanics

Cited by 1,999 publications

References 270 publications

Frequency-dependent complex modulus of the uterus: preliminary results

Frequency-dependent complex modulus of the uterus: preliminary results

The feasibility of using compression bioimpedance measurements to quantify peripheral edema

Viscoelastic properties of demineralized human dentin measured in water with atomic force microscope (AFM)-based indentation

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