Biomechanics refers to study of movement within dynamic biological systems. Advancement of computer software technologies such as JAVA language leads to combine stimuli and signals by biological systems and utilize them for research purposes. The main aim of this research is to analyse various biomechanical software and advancements that have been made in the field of mechanical software. Secondary research analysis has been utilized within this research paper. A Number of computational software such as OpenSim and ABAQUS have been proven to be very beneficial in this aspect. Advancement in biomechanical software has led to better research in cancer and cytoskeletal studies. Thus, Biomechanical software enables us to study kinetics of body without invasive procedures and does not cause any hindrance to ethical issues.