Biomedical applications of mid-infrared quantum cascade lasers – a review

Isensee, Katharina; Kröger-Lui, Niels; Petrich, Wolfgang

doi:10.1039/c8an01306c

Cited by 60 publications

(42 citation statements)

References 91 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…QCLs are now deployed for several applications [1], such as industrial process control, monitoring of pipeline leaks, emission control of pollutants and green-house gases, safety in workplaces and so on. In parallel, QCLs have been largely used in the research arena for breath analysis [2], study of gas kinetics in combustion processes [3], investigation of plasma [4] or supersonic expansion of gases [5] and precision spectroscopy [6]. In the latter respect QCLs were recognized early as excellent candidates for high-resolution applications because of a quantum noise limit of few hundred hertz [7].…”

Section: Introductionmentioning

confidence: 99%

Comb-calibrated sub-Doppler spectroscopy with an external-cavity quantum cascade laser at 77 μm

Alsaif¹,

Gatti²,

Lamperti³

et al. 2019

Opt. Express

View full text Add to dashboard Cite

Marangoni, M. (2019). Comb-calibrated sub-Doppler spectroscopy with an external-cavity quantum cascade laser at 77Abstract: We study the frequency noise and the referencing to a near-infrared frequency comb of a widely tunable external-cavity quantum-cascade-laser that shows a relatively narrow free-running emission linewidth of 1.7 MHz. The frequency locking of the laser to the comb further narrows its linewidth to 690 kHz and enables sub-Doppler spectroscopy on an N 2 O transition of the ν 1 band near 7.7 μm with sub-MHz resolution and absolute frequency calibration. The combined uncertainty on the measured transition center is estimated to be less than 50 kHz.

show abstract

Section: Introductionmentioning

confidence: 99%

Comb-calibrated sub-Doppler spectroscopy with an external-cavity quantum cascade laser at 77 μm

Alsaif¹,

Gatti²,

Lamperti³

et al. 2019

Opt. Express

View full text Add to dashboard Cite

show abstract

“…This finding highlights the prospect of using the transflection opto-fluidic interface in a future long-term implant. Table 4.1 compares the demonstrated results to other work using QCLs with respect to different measurement parameters such as the type of QCL, the wavenumber range, the environment of the substance and the concentrations measured [20]. In Figure 4.1 a visualization of the achieved glucose sensitivities related to the respective mean glucose concentration is presented.…”

Section: Long-term Stabilitymentioning

confidence: 98%

“…This fact hindered the selectivity for glucose in presence of other substances with absorption peaks in the same spectral region. Later experiments showed that this issue can be overcome with tunable external cavity (EC-) QCLs [15][16][17][18][19] and the method became a well established choice for the quantification of all sorts of substances in liquid environment in vitro [20].…”

Section: State Of the Art In Mid-infrared Based Glucose Monitoringmentioning

confidence: 99%

See 2 more Smart Citations

Towards a quantum cascade laser-based implant for the continuous monitoring of glucose

Isensee

Müller

Pucci

et al. 2018

Analyst

Self Cite

View full text Add to dashboard Cite

show abstract

Infrared detection of Criegee intermediates

Wang

Chang

Chung

2021

J Chinese Chemical Soc

View full text Add to dashboard Cite

In this mini‐review article, we present the recent progress of utilizing three types of infrared (IR) spectroscopic tools to investigate the chemistry of Criegee intermediates (CIs). The first part of this article described a recent work of Wang et al., which utilized rapid‐scan FTIR to detect CIs created from ozonolysis. The second part of this article describes the advantages of quantum cascade lasers (QCLs) used as novel IR spectroscopic tools to probe CIs and the key concepts of experimental implementations. We also summarize the works of Chang and co‐workers, which utilized distributed feedback QCLs with thermal chirping to detect the simplest CI, CH2OO, and the subsequent kinetics measurements, such as reactions of CH2OO with ozone, CH3SH, and dimethyl sulfoxide. In the last part of this article, we described the key ideas of external‐cavity QCLs coupled with off‐axis integrated cavity output spectroscopy, which was proposed by Chung et al., and also the latest progress on determination of the band strength of CH2OO and its rate coefficient with O3.

show abstract

Biomedical applications of mid-infrared quantum cascade lasers – a review

Abstract: Quantum cascade lasers with high spectral power density and narrow band emission profiles provide novel access to biomedical applications.

Cited by 60 publications

References 91 publications

Comb-calibrated sub-Doppler spectroscopy with an external-cavity quantum cascade laser at 77 μm

Comb-calibrated sub-Doppler spectroscopy with an external-cavity quantum cascade laser at 77 μm

Towards a quantum cascade laser-based implant for the continuous monitoring of glucose

Infrared detection of Criegee intermediates

Contact Info

Product

Resources

About