Biomolecule-assisted synthesis and functionality of metal nanoclusters for biological sensing: a review

Abstract

Schematic representation of the synthesis of biomolecule-assisted metal nanoclusters for biological sensing applications.

Synergistic integration of metal nanoclusters and biomolecules as hybrid systems for therapeutic applications

“…The interfacial chemistry has developed advantageous structure–property–performance relations that are crucial for their biomedical applications due to the atomic level management of the size, structure, composition, and surface of metal NCs. Recent research has primarily focused on the synthesis of various metal NCs by using coordination chemistry as the main strategy 33 , 36 , 37 , 38 . To a large extent, various biomolecules as stabilizing ligands to coordinate metal NCs have been extensively explored, such as proteins, peptides, DNA, and specific cells.…”

“…Moreover, metal-based drugs have been explored for their therapeutic performance, such as US Food and Drug Administration (FDA)-approved metallic drugs auranofin, a gold (I) compound used for the treatment of rheumatoid arthritis and cisplatin or cis- diamminedichloroplatinum (II) is used as a metal-based anticancer drug, have been explored for their therapeutic performance. To globalize precision medicine, bio-inspired metal NCs could be exploited as a universally therapeutic system to effectively integrate customizable biological effects (specificity, intrinsic bioactivity, and biodegradability) and tunable physicochemical properties (size, structure, and composition) 31 , 32 , 33 .…”

Synthesis of Highly Conductive Electrospun Recycled Polyethylene Terephthalate Nanofibers Using the Electroless Deposition Method

“…Electrospinning is a simple technique to produce fibers with diameters in the range of a few tens to hundreds of nanometers. Electrospun nanofibers have a range of applications such as food packaging, wound dressings, tissue engineering, water filtration [ 27 , 28 , 29 , 30 ], air filtration, facemasks, flexible electronics, and sensors [ 31 ]. Keeping in the broad scope of electrospun nanofibers, the aim of this study is to investigate the ELD performance on electrospun nanofiber to fabricate flexible and conductive materials.…”

Green Synthesis and Incorporation of Sericin Silver Nanoclusters into Electrospun Ultrafine Cellulose Acetate Fibers for Anti-Bacterial Applications

“…The novel metal (Au, Ag, Cu, and Pt) nanoclusters (NCs) composed of few to hundreds of atoms exhibited ultra-small sizes (<5 nm) that approach to the fermi wavelength of the conduction electrons. They show discrete energy levels, resulting in obvious fluorescence and molecule-like properties [ 15 , 16 ]. Thus, these NCs possess very unique properties than that of traditional metal nanoparticles and have attracted great attraction in recent years.…”