Bionics-Inspired Strong Coupling of Streptococcus-Like NiCo₂O₄ to Needle-Like MnO₂ for Enhanced Electrocatalytic Determination of Glucose

Abstract

Bionics-inspired streptococcus-like NiCo 2 O 4 coated needle-like MnO 2 architecture has been synthesized successfully, denoted as NiCo 2 O 4 -MnO 2 , and the nonenzymatic electrochemical sensor based on NiCo 2 O 4 -MnO 2 exhibits highly sensitive determination toward glucose. MnO 2 nanowires are regarded as effective nucleation sites, which allows uniformly growing of NiCo 2 O 4 as electrocatalytic centers on its surface by a hydrothermal method. The rational combination of streptococcus-like NiCo 2 O 4 and needle-like MnO 2 can effectively prevent the aggregation of nanomaterials due to the formation of 3D network, promote the electron transportation, and provide more electrocatalytic sites. The attractive nanostructure and composition were better confirmed by scanning electron microscopy, transmission electron microscopy and X-ray photoelectron spectroscopy, etc. The strong coupling of NiCo 2 O 4 -MnO 2 inspires the synergistic effect, showing a low detection limit of 0.036 μM (S/N = 3) for glucose in 0.1 M NaOH, a high sensitivity of 2887.57 μAmM −1 cm −2 and a wide response range (from 1 to 7100 μM). Moreover, the novel sensor exhibited high stability and good reproducibility. The sensor was highly selective to glucose in the presence of commonly interfering species like dopamine, uric acid, ascorbic acid, sodium chloride, fructose, galactose and mannose, and successfully applied to sensing glucose concentration in human serum samples.

Electrospun porous La–Sr–Co–Ni–O nanofibers for highly sensitive non-enzymatic glucose detection

“…8, although the sensitivity for those molecules is lower than that for glucose, these molecules also show linear response by the nonenzymatic biosensor. Similar behavior has also been reported for other metal oxide-based nonenzymatic glucose biosensors 27,28,38,[45][46][47][48][49] . Like most available glucose biosensors, glucose monitor interference by the coexisting biomolecules should be considered in real sample measurements 50 .…”

“…Similar behavior has also been reported for other metal oxide-based nonenzymatic glucose biosensors. 27,28,38,45–49 Like most available glucose biosensors, glucose monitor interference by the coexisting biomolecules should be considered in real sample measurements. 50 However, a biosensor that is sensitive to multiple carbohydrates may find application for multiple carbohydrates monitoring in human body fluid or fermentation processes.…”

NiCo2O4 Nano-/Microstructures as High-Performance Biosensors: A Review

“…Chen et al [ 271 ] synthesized bionics-inspired streptococcus-like mixed oxide NiCo 2 O 4 coated on needle-like MnO 2 architectures. Initially, MnO 2 nanowires were synthesized via a quick precipitation method, while NiCo 2 O 4 were grown on pre-synthesized MnO 2 nanowires via a facile hydrothermal method.…”

Development of SnO2@rGO Hybrid Nanocomposites through Complexometric Approach for Multi-Dimensional Electrochemical Application

“…20 To overcome these issues, non-enzymatic electrochemical sensor has founded as one of the most convenient methods with lots of merit. 21 Since, the non-enzymatic electro-oxidation performance of glucose depends upon the surface structure and morphology electrode materials. 22 Therefore, various attempts have been made by the researchers and academician to develop the non-enzymatic biosensors from many nano/microstructured materials (Ni, Cu, NiO, CuS, and SnO 2 etc.)…”