Biopharmaceutical Analysis of Coenzyme Q10 (Ubidecarenone)

Kalenikova, E. I.; Токарева, Мария Григорьевна; Gorodetskaya, E. A.; Galeeva, A. A.; Kibizova, E. M.; Медведев, О. С.

doi:10.1007/s11094-017-1529-z

Cited by 2 publications

(2 citation statements)

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“…summarises LCEC methods for the quantitation of UQ in biological samples. [34] They state such methods have advantages over other methods, including high selectivity and sensitivity. Franke et al employed coulometric detection for the determination of UQ/ubiquinol following LC separation, again as biomarkers of redox status and disease risk.…”

Section: Direct Detection Of Uqmentioning

confidence: 99%

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Ubiquinone electrochemistry in analysis and sensing

Conghaile

Arrigan

2022

Electrochemical Science Adv

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Ubiquinone (UQ) is a lipophilic compound present in most living organisms, where UQ's interesting but complex electrochemistry serves an important role in the transfer of electrons and protons within and across the mitochondrial membrane. We briefly review the electrochemical characteristics of UQ and its reduced state, ubiquinol, in solution and immobilized on electrodes, together with its application in electrochemical sensing and detection systems, for example, measuring redox status with reference to reactive oxidative species. The importance of the local environment, solvent, electrolyte, organic membrane, and pH, on the electrochemical behavior of UQ, is also discussed. We discuss techniques used for the direct detection of UQ such as liquid chromatographyelectrochemistry. Mediated electrochemistry of UQ allows for quantitative measurements of ions, small molecules, and other analytes such as glucose via chemical sensors and biosensors.

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Section: Direct Detection Of Uqmentioning

confidence: 99%

Section: Analytical Applications Of Uq Electrochemistrymentioning

confidence: 99%