Biopharmaceutical Application of Microwave Technology and the Scalability Concerns

Olalere, Olusegun Abayomi; Gan, Chee‐Yuen

doi:10.5812/jjnpp.121619

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…However, conventional extraction procedures have several drawbacks, including high costs, higher solvent consumption, longer extraction times, higher energy consumption, poorer degree of selectivity, and low-quality extracts (7,8). Given the long extraction duration of most conventional extraction techniques, the degradation of bioactive components in the plant material is unavoidably expected (9,10). Extreme heat might induce changes in the constituents of essential oils and eventual degradation of volatile compounds during the steam distillation and hydrodistillation extraction process (11,12).…”

Section: Overview Of Extraction Techniques Of Essential Oilsmentioning

confidence: 99%

Upscalability and Techno-economic Perspectives of Nonconventional Essential Oils Extraction Techniques

Olalere

Gan

Adeyi

et al. 2022

Jundishapur J Nat Pharm Prod

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Context: Nonconventional extraction methods, such as microwave, supercritical fluid, and ultrasonic, are known to be veritable means of producing solvent-free high-quality essential oils. Nonetheless, technical requirements for the utilization of these extraction technologies are often exorbitantly expensive, thereby limiting their utilization. Evidence Acquisition: Although these emerging extraction technologies have been reported to be efficient at a laboratory scale, their techno-economic analyses are necessary for proper upscaling. Scaling up nonconventional extraction has long been regarded as a critical constraint in larger industrial applications with a relatively limited body of published literature on more specific techno-economic analyses. Results: Therefore, an essential oil extraction unit’s techno-economic feasibility should be carefully assessed before an acquisition decision can be made for industrial upscaling. This review critically examined the implications of upscaling nonconventional extraction techniques while taking into consideration their techno-economic benefits. Conclusions: This study will undoubtedly assist researchers and industrial experts make an informed decision on the suitable extraction methods while taking into account the essential oil yield, quality characteristics, energy consumption, and operating costs.

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