Biophotonics applications of nanometric apertures

Wenger, Jérôme; Gérard, Davy; Lenne, P.-F.; Rigneault, H.; Bonod, Nicolas; Popov, Evgeny; Marguet, Didier; Nelep, Constantin; Ebbesen, Thomas W.

doi:10.1504/ijmpt.2009.025002

Cited by 6 publications

(5 citation statements)

References 69 publications

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“…Therefore, large BNAs offer advantages when special surface treatments are needed to anchor or immobilize biological molecules, especially for biological objects with large volumes that would obstruct their entrance into small nano-apertures. These results indicate that the BNA is a potential platform, similar to that offered by circular nano-apertures for biological applications at high molecule concentration, − ,, and that large BNAs present interesting performance. It should be noted that the fluorescence enhancement performance within BNAs can be optimized further by appropriate material and structure choice.…”

Section: Resultsmentioning

confidence: 75%

“…The plasmonic antennas also allow nanoscale control of the lifetime, − spectra, − and direction − of photon emissions. Many groups have already reported fluorescent emission enhancement from emitters located in the vicinity of different types of metallic nanostructures: metallic nanoparticles, ,, core–shell particles, nanoporous gold, hole arrays and metallic gratings, ,, and single nano-apertures. ,− …”

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confidence: 99%

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Plasmonic-Enhanced Molecular Fluorescence within Isolated Bowtie Nano-Apertures

Lü

Zhang

et al. 2012

ACS Nano

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We report experimental behaviors of polarization-dependent, plasmonic-enhanced molecular fluorescence within isolated bowtie nano-apertures (BNAs) milled in aluminum films. BNAs provide efficient control of the fluorescent count rate per molecule and the decay lifetime of the molecules and provide an effective detection volume at the nanometer scale by tuning either the excitation light polarization or the BNA size. Interestingly, large BNAs (>300 nm) present high plasmonic-enhanced fluorescence efficiency and can simultaneously confine the detection volume below the subdiffraction limit. Numerical simulations were performed that agreed qualitatively with the experimental results. The BNAs have potential applications, especially for single-molecule biological analysis.

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Section: Resultsmentioning

confidence: 75%

mentioning

confidence: 99%

Plasmonic-Enhanced Molecular Fluorescence within Isolated Bowtie Nano-Apertures

Lü

Zhang

et al. 2012

ACS Nano

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“…This limitation can be overcome by employing plasmonic antennas for light and two quintessential geometries have emerged for plasmon enhanced FCS: nano-apertures and nano-antennas. Small nano-apertures in a metal film [9,10], effectively block the background signal by an optically thick metal layer. They have proven to be very useful for FCS measurements [11][12][13][14] by shifting the limit of the highest concentration at which measurements are possible by 2-3 orders towards physiologically relevant concentrations [15].…”

Section: Introductionmentioning

confidence: 99%

Simple model for plasmon enhanced fluorescence correlation spectroscopy

Langguth¹,

Koenderink²

2014

Opt. Express

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Abstract:Metallic nano-antennas provide strong field confinement and intensity enhancement in hotspots and thus can ultimately enhance fluorescence detection and provide ultra small detection volumes. In solution-based fluorescence measurements, the diffraction limited focus driving the nano-antenna can outshine the fluorescence originating from the hotspot and thus render the benefits of the hotspot negligible. We introduce a model to calculate the effect of a nano-antenna, or any other object creating a nontrivial intensity distribution, for fluorescence fluctuation measurements. Approximating the local field enhancement of the nano-antenna by a 3D Gaussian profile, we show which hotspot sizes and intensities are the most beneficial for an FCS measurement and compare it to realistic antenna parameters from literature. 11, 637-644 (2011). 13. J. Wenger, H. Rigneault, J. Dintinger, D. Marguet, and P.-F. Lenne, "Single-fluorophore diffusion in a lipid membrane over a subwavelength aperture," J.

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“…Nevertheless, gold offered some new opportunities to examine not only the SER response, but also the flow of electromagnetic energy in periodic dielectric apertures containing metal nanoparticles. This construct differs from the widely studied nanohole array in metal films [15][16][17]21 . Accordingly, we conducted Finite Difference Time Domain (FTDT) calculations to examine the optical field response to gold nanoparticles distributed in a rectangular array of dielectric cavities.…”

Section: Methodsmentioning

confidence: 99%

Nanoplasmonic photonic crystal diatoms and phytoliths

et al. 2011

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Evidence is emerging that silica-containing plant cells (phytoliths) and single cell micro-organisms (diatoms) exhibit optical properties reminiscent of photonic crystals. In the latter biosilicates, these properties appear to arise from light interactions with the intricate periodic patterns of micro-and nano-pores called foramina that are distributed over the frustule (outer silica shell). In this report, we show that Nitzschia Closterium pennate diatom frustules can be used to template arrays of nanoplasmonic particles to confer more complex physical properties, as shown by simulation and experiment. Selective templating of silver and gold nanoparticles in and around the array of pores was achieved by topochemical functionalization with nanoparticles deposited from solution, or by differential wetting/dewetting of evaporated gold films. The nanoplasmonic diatom frustules exhibit surface enhanced Raman scattering from chemisorbed 4-aminothiophenol. Thermally induced dewetting of gold films deposited on a frustule produces two classes of faceted gold nanoparticles. Larger particles of irregular shape are distributed with some degree of uniaxial anisotropy on the surface of the frustule. Smaller particles of more uniform size are deposited in a periodic manner in the frustule pores. It is thought that surface curvature and defects drive the hydrodynamic dewetting events that give rise to the different classes of nanoparticles. Finite difference time domain calculations on an idealized nanoplasmonic frustule suggest a complex electromagnetic field response due to coupling between localized surface plasmon modes of the nanoparticles in the foramina and an overlayer gold film.

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Biophotonics applications of nanometric apertures

Cited by 6 publications

References 69 publications

Plasmonic-Enhanced Molecular Fluorescence within Isolated Bowtie Nano-Apertures

Plasmonic-Enhanced Molecular Fluorescence within Isolated Bowtie Nano-Apertures

Simple model for plasmon enhanced fluorescence correlation spectroscopy

Nanoplasmonic photonic crystal diatoms and phytoliths

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