2015
DOI: 10.1002/uog.15663
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Biophysical and biochemical markers at 35-37 weeks' gestation in the prediction of adverse perinatal outcome

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Cited by 63 publications
(67 citation statements)
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References 28 publications
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“…The results of this study are consistent with those of the only two previous screening studies in unselected populations that examined biomarkers of impaired placentation in 8268 pregnancies at 30–34 weeks' gestation and 3953 at 35–37 weeks for prediction of adverse perinatal outcome; in both studies, these markers were useful in the prediction of PE and delivery of a SGA neonate, but not of adverse events in labor or after delivery.…”
Section: Discussionsupporting
confidence: 88%
“…The results of this study are consistent with those of the only two previous screening studies in unselected populations that examined biomarkers of impaired placentation in 8268 pregnancies at 30–34 weeks' gestation and 3953 at 35–37 weeks for prediction of adverse perinatal outcome; in both studies, these markers were useful in the prediction of PE and delivery of a SGA neonate, but not of adverse events in labor or after delivery.…”
Section: Discussionsupporting
confidence: 88%
“…Maternal and biochemical markers become more important for the prediction of PE in late pregnancy. Thus, among several potential factors, mean arterial pressure, PlGF and sFlt-1 were the ones associated with the prediction of PE between 30-34 weeks 81 and 35-37 weeks 82 . In contrast, the addition of uterine artery PI and maternal cardiovascular parameters did not improve the prediction of PE after 35-36 weeks 83 .…”
Section: Recommendationsmentioning
confidence: 88%
“…In contrast to the early onset data, the predictive ability for term preeclampsia was quite poor. These data suggest a concept of 2-stage screening with screening in first or early second trimester for early onset disease and with screening during 3 rd trimester for late onset disease may be a more fruitful strategy 39,40 ,. As the authors correctly point out, this study represents one of the most comprehensive evaluations of putative biomarkers in early pregnancy to predict preeclampsia, using a rigorous prospective cohort design and with robust immunoassays on a Luminex platform.…”
Section: Biomarkers For Early Pregnancy Prediction Of Preeclampsiamentioning
confidence: 90%