Biophysical characterization of the interaction between human serum albumin and n-dodecyl β-d-maltoside: A multi-technique approach

Molecular Interaction of Amino Acid-Based Gemini Surfactant with Human Serum Albumin: Tensiometric, Spectroscopic, and Molecular Docking Study

“…Proteins are most critical constituents of life that plays an important role in living species and have a tendency to combine with inorganic/organic moieties, for example, fatty acids, hematin, bilirubin, surfactants, metal ions, and drugs. − The interaction of protein–surfactant played a vital role in a broad variety of industrial aspects, for example, biotechnological and biosciences processes, gene delivery, drug delivery, coatings, cosmetics, food industry, and production of pharmaceutical materials such as blood serum, a blend of human serum albumin (HSA) with an integer of compounds, comprising small molecular surface-active molecules. The surface tension of such biological fluids is used as a diagnostic and therapeutic device …”

Fluorescent delivery vehicle containing cobalt oxide–umbelliferone nanoconjugate: DNA/protein interaction studies and anticancer activity on MF7 cancer cell line

“…12). 23,45 Table 2 Stern-Volmer quenching constants, binding parameters and thermodynamic parameters for the interaction of HSA with the nanoconjugate at various temperatures…”

Insights into the interaction mechanism between tiagabine hydrochloride and two serum albumins

“…Peak 2 (l ex ¼ 280 nm, l em ¼ 338 nm for HSA and l ex ¼ 280 nm, l em ¼ 340 nm for BSA) mainly reveals the spectral behavior of tryptophan and tyrosine residues and reects the polarity of the HSA microenvironment. 40,41 By comparing and analyzing the position of the excitation and emission wavelength, and the Stokes shi ( Table 2) of TGB-HSA complex in the absence and presence of TGB, it could be seen that both peak 1 and 2 were nearly unchanged, which indicated that the molecular microenvironment around the uorophore residues of HSA was almost unaffected by TGB. Similarly, the microenvironment of BSA was not obviously perturbed by TGB either, as the Stokes shi of BSA had no signicant change.…”