Biopolymers in Medical Implants

Bhatt, Rachana; Jaffé, Michael

doi:10.1007/978-3-319-20206-8_11

Cited by 12 publications

(5 citation statements)

References 206 publications

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“…Scaffolds based on bioceramics such as calcium phosphates are preferred candidates for medical implants. 20 To explore the integration of bioceramics into ELMs, we employed a bacterial mineralization system based on a modified version of the wellknown phosphatase PhoA. 21 Three engineered variants of E. coli strain DH10B were examined: PhoA, E6/PhoA, and Triblock/PhoA.…”

Section: Analysis Of Alkaline Phosphatase (Phoa)-catalyzed Calcium Ph...mentioning

confidence: 99%

Quantitative Real-Time Analysis of Living Materials by Stimulated Raman Scattering Microscopy

Qian,

Liu,

Chittur

et al. 2024

Anal. Chem.

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Composite materials built in part from living organisms have the potential to exhibit useful autonomous, adaptive, and self-healing behavior. The physicochemical, biological, and mechanical properties of such materials can be engineered through the genetic manipulation of their living components. Successful development of living materials will require not only new methods for design and preparation but also new analytical tools that are capable of real-time noninvasive mapping of chemical compositions. Here, we establish a strategy based on stimulated Raman scattering microscopy to monitor phosphatase-catalyzed mineralization of engineered bacterial films in situ. Real-time label-free imaging elucidates the mineralization process, quantifies both the organic and inorganic components of the material as functions of time, and reveals spatial heterogeneity at multiple scales. In addition, we correlate the mechanical performance of films with the extent of mineralization. This work introduces a promising strategy for quantitatively analyzing living materials, which should contribute to the accelerated development of such materials in the future.

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Section: Analysis Of Alkaline Phosphatase (Phoa)-catalyzed Calcium Ph...mentioning

confidence: 99%

Quantitative Real-Time Analysis of Living Materials by Stimulated Raman Scattering Microscopy

Qian,

Liu,

Chittur

et al. 2024

Anal. Chem.

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“…Poly-beta-hydroxybutyrate has also been used as a material for surgical implants and cell culture scaffolds. 246,247 A novel glycan polysaccharide produced from a marine species (Athelia sp.) has immense potential to enhance heavy oil recovery in hightemperature and high-salinity reservoirs 248 (Figure 9).…”

Section: Commercial Applications Of Microbial Biopolymersmentioning

confidence: 99%

“…PHAs have also been used extensively as implants in the esophagus, vascular cartilage, and nerves. Poly‐beta‐hydroxybutyrate has also been used as a material for surgical implants and cell culture scaffolds 246,247 . A novel glycan polysaccharide produced from a marine species ( Athelia sp.)…”

Section: Challenges and Future Directionsmentioning

confidence: 99%

A comprehensive review on developments and future perspectives of biopolymer‐based materials for energy storage

Mahajan,

Sharma

2024

Energy Storage

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Driven by the escalating environmental impact of synthetic materials, there has been a growing focus on employing eco‐sustainable biomass‐derived biopolymers and native materials as a viable alternative to traditional energy storage applications. Biopolymer‐based energy devices, like batteries, supercapacitors, electrode materials, and ion‐exchange membranes, a novel and eco‐conscious approach, hold great potential for flexible and smart electrochemical energy storage and conversion devices, owing to their affordability, environmental sustainability, and biodegradability. This critical review outlines the sources and properties of biopolymers leading to energy storage and emphasizes their utilization in the energy sector. Despite their inherent constraints, biopolymers can be effectively leveraged when combined with other materials in composites. This collaborative approach not only refines their intrinsic physical attributes but also elevates the electrochemical performance of biologically active molecules. In this regard, bionanocomposites, a class of materials combining biopolymers and nanoparticles, have emerged as a promising greener alternative to conventional petroleum‐based polymers. Their biocompatibility, biodegradability, and antimicrobial properties have promoted their increased commercialization, thus paving the way for a more sustainable future. The review concludes by identifying and effectively addressing the limitations, challenges, and future perspectives of biopolymers in energy storage applications.

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“…The most commonly used artificial implants contain knees, hips, eyes, heart, ears, cardiovascular, and breasts etc. [181] Biopolymer centered materials play a significant part for the fabrication of medical implementable appliances via cell proliferation, seeding and restoration of fresh tissues in the form of 3d scaffolds, thus screening immense potential in study of tissue engineering. [182] One of the most important features of bio-polymers is their presence in large abundance and small immunogenic behavior.…”

Section: Biopolymeric Materials In Medical Implantsmentioning

confidence: 99%

Multifunctional Biopolymers‐Based Composite Materials for Biomedical Applications: A Systematic Review

2021

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Biopolymers are considered as a favorable group of substances with a broad array of applications, of which biomedical field stands out. The interesting features of biopolymers such as low‐cost, non‐cytotoxicity, hydrophilicity, biodegradation and biocompatibility make them promising and excellent feedstock to be used in implantable devices. The bounteous reactive functional groups in the backbone structure of polysaccharides and its derivatives could be utilized to develop hydrogels, nano‐composite and 3D scaffolds with appealing structures and desired features, leading to promising research attention towards biomedical fields. The present review describes the foremost properties as well as potential of different biopolymers, and their composites for application in implantable biomedical systems. This work may introduce readers about the comprehension of state‐of‐the‐art advances, real present challenges along with the future anticipation of eco‐friendly and biomimetic techniques for the modification of biopolymeric materials to improve their biomedical applications.

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Biopolymers in Medical Implants

Cited by 12 publications

References 206 publications

Quantitative Real-Time Analysis of Living Materials by Stimulated Raman Scattering Microscopy

Quantitative Real-Time Analysis of Living Materials by Stimulated Raman Scattering Microscopy

A comprehensive review on developments and future perspectives of biopolymer‐based materials for energy storage

Multifunctional Biopolymers‐Based Composite Materials for Biomedical Applications: A Systematic Review

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