Bioprinting of Nerve

Owens, Christopher M.; Marga, Françoise; Forgács, Gabor

doi:10.1016/b978-0-12-800972-7.00023-2

Cited by 5 publications

(2 citation statements)

References 62 publications

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“…Despite the extensive materials that have been investigated for 3D neural cell culture, some of them cannot be easily manipulated by printing. Currently available materials are mainly alginate [161][162][163], Poly(ethylene glycol) diacrylate (PEGDA) [164], fibrin [165], chitosan [166][167][168][169], hyaluronic acid [170], silk fibroin [171][172][173], gelatin [174][175][176], agarose [177], methycellulose [178,179], collagen [180,181],etc. Several detailed reviews have illustrated the properties of these available bioinks from various perspectives [160,182,183].…”

Section: Bioink and Printing Strategiesmentioning

confidence: 99%

3D neural tissue models: From spheroids to bioprinting

et al. 2018

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Section: Bioink and Printing Strategiesmentioning

confidence: 99%

3D neural tissue models: From spheroids to bioprinting

et al. 2018

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“…Advancements in tissue engineering, based on its underlying science [3] and technology [4], have opened new avenues for clinical applications [5]. Both scaffold-free and scaffold-based tissue engineering techniques have demonstrated the capability to enhance medical treatment [6][7][8][9][10][11]. Despite major advances in the field, many drawbacks of using current technologies remain unaddressed.…”

Section: Introductionmentioning

confidence: 99%

Energy Band Gap Investigation of Biomaterials: A Comprehensive Material Approach for Biocompatibility of Medical Electronic Devices

et al. 2020

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Over the past ten years, tissue engineering has witnessed significant technological and scientific advancements. Progress in both stem cell science and additive manufacturing have established new horizons in research and are poised to bring improvements in healthcare closer to reality. However, more sophisticated indications such as the scale-up fabrication of biological structures (e.g., human tissues and organs) still require standardization. To that end, biocompatible electronics may be helpful in the biofabrication process. Here, we report the results of our systematic exploration to seek biocompatible/degradable functional electronic materials that could be used for electronic device fabrications. We investigated the electronic properties of various biomaterials in terms of energy diagrams, and the energy band gaps of such materials were obtained using optical absorption spectroscopy. The main component of an electronic device is manufactured with semiconductor materials (i.e., Eg between 1 to 2.5 eV). Most biomaterials showed an optical absorption edge greater than 2.5 eV. For example, fibrinogen, glycerol, and gelatin showed values of 3.54, 3.02, and 3.0 eV, respectively. Meanwhile, a few materials used in the tissue engineering field were found to be semiconductors, such as the phenol red in cell culture media (1.96 eV energy band gap). The data from this research may be used to fabricate biocompatible/degradable electronic devices for medical applications.

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Current progress, challenges, and future prospects of testis organoids†

Cham

Chen

Honaramooz

2021

Biology of Reproduction

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Spermatogenic failure is believed to be a major cause of male infertility. The establishment of a testis organoid model would facilitate the study of such pathological mechanisms and open the possibility of male fertility preservation. Due to the complex structures and cellular events occurring within the testis, the establishment of a compartmentalized testis organoid with a complete spermatogenic cycle remains a challenge in all species. Since the early 20th century, a great variety of scaffold-based and scaffold-free testis cell culture systems have been established to recapitulate de novo testis organogenesis and in vitro spermatogenesis. The utilization of the hydrogel scaffolds provides a 3D microenvironment for testis cell growth and development, facilitating the reconstruction of de novo testis tissue-like structures and spermatogenic differentiation. Using a combination of different strategies, including the use of various scaffolding biomaterials, the incorporation of the living cells with high self-assembling capacity, and the integration of the advanced fabrication techniques, a scaffold-based testis organoid with a compartmentalized structure that supports in vitro spermatogenesis may be achieved. This article briefly reviews the current progress in the development of scaffold-based testis organoids while focusing on the scaffolding biomaterials (hydrogels), cell sources, and scaffolding approaches. Key challenges in current organoid studies are also discussed along with recommendations for future research.

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Bioprinting of Nerve

Cited by 5 publications

References 62 publications

3D neural tissue models: From spheroids to bioprinting

3D neural tissue models: From spheroids to bioprinting

Energy Band Gap Investigation of Biomaterials: A Comprehensive Material Approach for Biocompatibility of Medical Electronic Devices

Current progress, challenges, and future prospects of testis organoids†

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