2016
DOI: 10.4155/tde-2015-0011
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Bioproduction of Gold Nanoparticles for Photothermal Therapy

Abstract: These gold nanoparticles can be synthesized with reproducibility, modified with seemingly limitless chemical functional groups, with adequate controlled optical properties for laser phototherapy of tumors and targeted drug delivery.

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Cited by 41 publications
(62 citation statements)
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“…Gold nanoparticles were prepared according to a seed-growth method [21,35]. An aqueous extract of Plectranthus saccatus (Benth.…”
Section: Discussionmentioning
confidence: 99%
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“…Gold nanoparticles were prepared according to a seed-growth method [21,35]. An aqueous extract of Plectranthus saccatus (Benth.…”
Section: Discussionmentioning
confidence: 99%
“…Firstly, the cell viability in normal-like human keratinocytes (HaCaT cell line) was tested in order to verify if our nanoparticles were safe when in contact with a healthy non-cancer tissue (see Fig 13). Statistical analysis was based on Student’s t-test for comparisons between cell viability values with non-conjugated HAOA-coated gold nanoparticles [21] and EGF-conjugated HAOA-coated nanoparticles (present work). No significant differences (p > 0.05) were found between the viability of HaCat cells treated with HAOA-coated gold nanoparticles and EGF-conjugated HAOA-coated gold nanoparticles at equal concentrations.…”
Section: Discussionmentioning
confidence: 99%
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“…A variety of inorganic and organic nanomaterials have been applied in the study of PTT because of their good light–heat conversion abilities. Gold nanomaterials have become a research focus in recent years because of their many advantages, such as ease of synthesis, characterization, and modification; excellent light‐heat conversion capability; and good biocompatibility . Lu et al .…”
Section: Optical Treatment For Melanomamentioning
confidence: 99%
“…Gold nanomaterials have become a research focus in recent years because of their many advantages, such as ease of synthesis, characterization, and modification; excellent lightheat conversion capability; and good biocompatibility. 100 Lu et al synthesized a hollow gold nanoparticle containing a small molecular peptide ([Nle4, D-Phe7]a-MSH) that successfully targeted F10/B16 melanoma cells and played a positive role in hyperthermal ablation under near infrared laser irradiation. 101 In animal experiments, Heidari et al exposed gold-ferrite nanoparticles to an 808 nm near-infrared laser.…”
Section: Photothermal Therapymentioning
confidence: 99%