Biopsy of the oral mucosa: Does size matter?

Lazzarotto, Benjamin; Garcia, Chloé; Martinelli-Kläy, Carla Patrícia; Lombardi, Tommaso

doi:10.1016/j.jormas.2022.02.005

Cited by 5 publications

(3 citation statements)

References 11 publications

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“…28 Moreover, enough size and amounts of tissue are better to be obtained for adequate histopathological examination to reach an accurate and definitive diagnosis. 28 , 29 However, clinically the locations of oral lesions, such as the floor of mouth, esthetic zone of the lip, gingiva, and the mental area, may potentially hinder the biopsy tissues' sampling due to access, hemostasis, and possibly injury to submandibular duct or mental nerve. 28…”

Section: General Principles Of Oral Biopsymentioning

confidence: 99%

Oral soft tissue biopsy surgery: Current principles and key tissue stabilization techniques

Jeng,

Chang,

Chiang

et al. 2024

Journal of Dental Sciences

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Section: General Principles Of Oral Biopsymentioning

confidence: 99%

Oral soft tissue biopsy surgery: Current principles and key tissue stabilization techniques

Jeng,

Chang,

Chiang

et al. 2024

Journal of Dental Sciences

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“…Therefore, the search for cytological markers-indicators of the individual state of oral mucosa is promising not only for improving the quality of diagnosis and correction of dental status, but also for determining the general somatic health of patients. It has been clinically proven that the mucous membrane is the most accurate indicator for assessing the pathological processes of the digestive tract, the immune status of the body, the general level of activity and proliferation of cellular systems [3].At a young age, diseases of the oral mucosa develop against the background of decreased salivation and local tissue resistance, disruption of the processes of differentiation and keratinization of epithelial cells, as well as changes in the microbiocenosis of the mucous membrane [4,5].In connection with the above, in the treatment of diseases of the oral mucosa, it is important to include in the complex of diagnostic and preventive measures that are minimally invasive and accessible at a dental appointment and would help accelerate the restoration of the mucous barrier and microcirculation, while having minimal side effects on the body in general and providing the possibility of dynamic observation [6,7,8].…”

mentioning

confidence: 99%

“…In connection with the above, in the treatment of diseases of the oral mucosa, it is important to include in the complex of diagnostic and preventive measures that are minimally invasive and accessible at a dental appointment and would help accelerate the restoration of the mucous barrier and microcirculation, while having minimal side effects on the body in general and providing the possibility of dynamic observation [6,7,8].…”

mentioning

confidence: 99%

Approaches to the Issue of Screening for Diseases of the Oral Mucosa: A Present View

Bilozetskyi,

Radchuk,

Dzetsiukh

2023

Ukr. Dent. Alm.

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Pathological processes in the oral mucosa in the structure of visits to the therapeutic dentistry clinic occupy a significant niche among all initial visits. In this regard, in the treatment of diseases of the oral mucosa, it is important to include in the complex of diagnostic and preventive measures, which would make it possible to diagnose the pathological process at the preclinical stage, and would be characterized by minimally invasiveness, long-term accuracy, ease of use and would help accelerate the recovery of the mucous membrane. and microcirculation, while having minimal side effects on the body as a whole and providing the possibility of dynamic observation. The purpose of the research is to analyze literature sources in order to comprehensively monitor modern approaches to the issue of screening for diseases of the oral mucosa. Materials and methods. Review and analysis of scientific and medical literature based on Scopus, Web of Science, MedLine, PubMed, NCBI databases, the study of which does not exceed 5-7 years, including literature reviews and results of clinical studies. Research results. In a number of nosological units, changes in the oral mucosa are of a specific nature, when the appearance can make a diagnosis and determine treatment tactics. However, in most cases, the diagnosis of diseases manifested in the oral mucosa is complicated, since the clinical picture is nonspecific and is often aggravated by additional unfavorable local factors. The cellular composition from the lesion, reflecting the dynamics of changes in the mucous membrane during its epithelization, is one of the objective tests for assessing the general condition of the body. Therefore, the study of the processes of differentiation of oral mucosa with an in-depth analysis of the cytological features of various anatomical areas in normal conditions and morphological and cytospecific changes in the presence of an inflammatory process in periodontal tissues is a relevant and promising area of research.

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Pearls and pitfalls in the diagnosis of small oral biopsies

McNamara

Kalmar²

2023

Seminars in Diagnostic Pathology

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Biopsy of the oral mucosa: Does size matter?

Cited by 5 publications

References 11 publications

Oral soft tissue biopsy surgery: Current principles and key tissue stabilization techniques

Oral soft tissue biopsy surgery: Current principles and key tissue stabilization techniques

Approaches to the Issue of Screening for Diseases of the Oral Mucosa: A Present View

Pearls and pitfalls in the diagnosis of small oral biopsies

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