Biosensors for detection of organophosphate pesticides: Current technologies and future directives

Kumaran, Akash; Vashishth, Roopal; Singh, Siya; Surendran, U.; James, Anina; Chellam, Padmanaban Velayudhaperumal

doi:10.1016/j.microc.2022.107420

Cited by 36 publications

(8 citation statements)

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, in most cases, these pesticides are also toxic to nontarget organisms, including humans. Therefore, the monitoring of pesticide residue levels is critical for human health and environmental security [ 51 ]. Borah et al fabricated an amperometric biosensor for pesticides by immobilizing glutathione-S-transferase on a platinum electrode coated with a graphene oxide–gelatin matrix and crosslinked with glutaraldehyde [ 52 ].…”

Section: Gelatin As a Matrix For Immobilized Biorecognition Materialsmentioning

confidence: 99%

Applications of Gelatin in Biosensors: Recent Trends and Progress

Guan

Huang

2022

Biosensors

View full text Add to dashboard Cite

Gelatin is a natural protein from animal tissue with excellent biocompatibility, biodegradability, biosafety, low cost, and sol–gel property. By taking advantage of these properties, gelatin is considered to be an ideal component for the fabrication of biosensors. In recent years, biosensors with gelatin have been widely used for detecting various analytes, such as glucose, hydrogen peroxide, urea, amino acids, and pesticides, in the fields of medical diagnosis, food testing, and environmental monitoring. This perspective is an overview of the most recent trends and progress in the development of gelatin-based biosensors, which are classified by the function of gelatin as a matrix for immobilized biorecognition materials or as a biorecognition material for detecting target analytes.

show abstract

Section: Gelatin As a Matrix For Immobilized Biorecognition Materialsmentioning

confidence: 99%

Applications of Gelatin in Biosensors: Recent Trends and Progress

Guan

Huang

2022

Biosensors

View full text Add to dashboard Cite

show abstract

“…However, they cannot meet the needs of grassroots supervision, market, and household daily inspection owing to the complexity of raw sample preprocessing, expensive instruments, complicated procedures, and other operational constraints. Electrochemical biosensors offer many advantages, including ease-of-use, cost-effectiveness, high sensitivity, and rapid detection, and have become alternative devices for pesticide detection [ 8 , 9 , 10 ]. Compared to other analytical methods, they can address long analysis time and extensive sample handling, making them popular in FT detection.…”

Section: Introductionmentioning

confidence: 99%

NH2-MIL-125(Ti)/Reduced Graphene Oxide Enhanced Electrochemical Detection of Fenitrothion in Agricultural Products

Shu

Zou

et al. 2023

Foods

View full text Add to dashboard Cite

The abuse of organophosphate pesticides causes serious threats to human health, which threatens approximately 3 million people and leads to more than 2000 deaths each year. Therefore, it is necessary to determine the residue of fenitrothion (FT) in environmental and food samples. Herein, we developed a non-enzymatic electrochemical sensor with differential pulse voltammetry signal output to determine FT in model solutions and spiked samples. Delicately, the sensor was designed based on the fabrication of hydrothermally synthesized titanium-based metal-organic frameworks (MOFs) material (NH2-MIL-125(Ti))/reduced graphene oxide (RGO) (NH2-MIL-125(Ti)/RGO) nanocomposites for better target enrichment and electron transfer. The peak response of differential pulse voltammetry for FT under optimized conditions was linear in the range of 0.072–18 μM with the logarithm of concentrations, and the detection limit was 0.0338 μM. The fabricated sensor also demonstrated high stability and reproducibility. Moreover, it exhibited excellent sensing performances for FT in spiked agricultural products. The convenient fabrication method of NH2-MIL-125(Ti)/RGO opens up a new approach for the rational design of non-enzymatic detection methods for pesticides.

show abstract

“…Acetylcholinesterase (AChE) biosensors have emerged as a promising technique for pesticides monitoring during the past about twenty years. [3][4][5][6][7][8][9][10][11] These biosensors have been an alternative to the traditional techniques including MS, GC-MS and HPLC by simplifying or canceling sample pre-treatment, thereby reducing the analysis time and cost. AChE immobilized on the electrode surface can catalyze the hydrolysis of acetylthiocholine chloride (ATCl), then the produced electrically active thiocholine (TCl) can result in an irreversible oxidation peak.…”

Section: Introductionmentioning

confidence: 99%

“…Acetylcholinesterase (AChE) biosensors have emerged as a promising technique for pesticides monitoring during the past about twenty years [3–11] . These biosensors have been an alternative to the traditional techniques including MS, GC‐MS and HPLC by simplifying or canceling sample pre‐treatment, thereby reducing the analysis time and cost.…”

Section: Introductionmentioning

confidence: 99%

Efficient Immobilization of Acetylcholinesterase onto Amino Functionalized Nitrogen‐doped Reduced Graphene Oxide for Highly Sensitive Pesticides Biosensors

Li,

Zhao,

Wang

et al. 2023

ChemistrySelect

View full text Add to dashboard Cite

The residues of carbamates pesticides can cause a threat to human and animal health. Therefore, the exact and speedy detection of pesticides is very urgent. In this work, a novel acetylcholinesterase (AChE) biosensor based on amino functionalized nitrogen‐doped reduced graphene oxide (NrGO−NH2) has been developed for the determination of carbamates pesticides. The NrGO−NH2 can not only serve as electronic bridges and signal amplifiers, but also efficiently immobilize AChE. The detection linear range for carbofuran is ranged from 0.05 to 11 ng/mL, and the detection limit is 0.025 ng/mL. Under the optimum conditions, the developed biosensor has also been successfully used for pesticide residues detecting in vegetable samples.

show abstract

Biosensors for detection of organophosphate pesticides: Current technologies and future directives

Cited by 36 publications

References 85 publications

Applications of Gelatin in Biosensors: Recent Trends and Progress

Applications of Gelatin in Biosensors: Recent Trends and Progress

NH2-MIL-125(Ti)/Reduced Graphene Oxide Enhanced Electrochemical Detection of Fenitrothion in Agricultural Products

Efficient Immobilization of Acetylcholinesterase onto Amino Functionalized Nitrogen‐doped Reduced Graphene Oxide for Highly Sensitive Pesticides Biosensors

Contact Info

Product

Resources

About