Biosynthesis of silver nanoparticles using <i>Caesalpinia ferrea</i> (Tul.) Martius extract: physicochemical characterization, antifungal activity and cytotoxicity

Soares, Monica; Corrêa, Rafael O.; Stroppa, Pedro Henrique Fazza; Marques, Flávia C.; Andrade, Gustavo F. S.; Corrêa, Charlane C.; Brandão, Marcos Antônio Fernandes; Raposo, Nádia Rezende Barbosa

doi:10.7717/peerj.4361

Cited by 34 publications

(19 citation statements)

References 53 publications

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“…The significant enhancement of the signal at 1000 cm −1 (due to ring breathing and asymmetric stretching vibration of CH 2 in the skeletal chain of PI, TCA, and biomolecules from plant extract) reveals that the CH 2 chain is close to the surface of AgNPs. The results of our SERS analysis are in agreement with previous reports and discussions above [102][103][104][105][106]. The nanocolloidal sample Cinn-AgNP-PI is SERS-inactive ( Figure 9d).…”

Section: Discussionsupporting

confidence: 92%

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

et al. 2020

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The emergence of resistant pathogens is a burden on mankind and threatens the existence of our species. Natural and plant-derived antimicrobial agents need to be developed in the race against antibiotic resistance. Nanotechnology is a promising approach with a variety of products. Biosynthesized silver nanoparticles (AgNP) have good antimicrobial activity. We prepared AgNPs with trans-cinnamic acid (TCA) and povidone-iodine (PI) with increased antimicrobial activity. We synthesized also AgNPs with natural cinnamon bark extract (Cinn) in combination with PI and coated biodegradable Polyglycolic Acid (PGA) sutures with the new materials separately. These compounds (TCA-AgNP, TCA-AgNP-PI, Cinn-AgNP, and Cinn-AgNP-PI) and their dip-coated PGA sutures were tested against 10 reference strains of microorganisms and five antibiotics by zone inhibition with disc-and agar-well-diffusion methods. The new compounds TCA-AgNP-PI and Cinn-AgNP-PI are broad spectrum microbicidal agents and therefore potential coating materials for sutures to prevent Surgical Site Infections (SSI). TCA-AgNP-PI inhibits the studied pathogens stronger than Cinn-AgNP-PI in-vitro and on coated sutures. Dynamic light scattering (DLS), ultraviolet-visible spectroscopy (UV-Vis), Fourier Transform infrared spectroscopy (FT-IR), Raman, X-ray diffraction (XRD), microstructural analysis by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) confirmed the composition of TCA-AgNP-PI and Cinn-AgNP-PI. Smart solutions involving hybrid materials based on synergistic antimicrobial action have promising future perspectives to combat resistant microorganisms.Pharmaceutics 2020, 12, 361 2 of 36 20,000 related deaths in the United States in 2017 only and remains to be one of the important infection-associated mortality reasons [11,12]. The formation of biofilms on biotic and abiotic surfaces [13] paved the way for biofilm antibiotic tolerance as another major health threat [14,15]. This additional problem hampers the treatment of infections, most often gives rise to chronic infections, in the worst case to therapeutic failure, severe morbidity, and mortality [4]. More than 80% of microbial infections are caused by microbial biofilm formation and pose a severe health risk because treatment with antibiotics remains ineffective [16]. The incidence of chronic wound infections is increasing globally to alarming levels [17]. Chronic wounds are marked by high bacterial colonization and infection rates, which can be treated only by novel therapeutic approaches other than the use of conventional antibiotics [18,19]. Chronic wound tissues can contain microbiomes of complex communities with coexisting fungal and bacterial colonies of different strains within biofilms [20]. According to this inter-kingdom model, fungi like Candida albicans can offer structures for other bacteria (S. aureus, P. aeruginosa, Streptococcus spp., E. faecalis, E. coli, and Acinetobacter baumannii etc.) to attach, form intricate biofilms, and increase the resistance against any ...

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Section: Discussionsupporting

confidence: 92%

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

et al. 2020

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“…The zone of inhibition values obtained here is similar to those reported by Yasir et al 10 The MICs values of ScAgNPs against all tested Candida and bacteria species ranged from 0.125-0.250 mg/mL, whereas the MBCs and MFCs were 0.250 and 0.500 mg/mL, respectively. In a recent study, 17 AgNPs synthesized by Caesalpinia ferrea seed extract showed MIC values in the range of 156.25-1,250 µg/mL, and MFC values in the range of 312.5-5,000 µg/mL against C. albicans, C. glabrata, C. kruzei, and C. guilliermondii. 17 The MIC and MFC results of the present study demonstrate that the ScAgNPs exhibited high anticandidal activity.…”

Section: Antimicrobial Activity Of Scagnpsmentioning

confidence: 98%

“…The antimicrobial activity of biogenic AgNPs was well documented in the literature. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] However, there are very few studies available in the literature on the inhibition of production of various extracellular hydrolytic enzymes and germ tubes in Candida spp by nanoparticles. [22][23][24] Due to the scarcity in the literature on the inhibition of production of various virulence factors by Candida spp, herein for the first time we have reported the potent inhibitory effects of green synthesized AgNPs on the production of different virulence attributes of Candida species isolated from oropharyngeal mucosa of HIV patients.…”

Section: Introductionmentioning

confidence: 99%

<p>Anticandidal activity of biosynthesized silver nanoparticles: effect on growth, cell morphology, and key virulence attributes of Candida species</p>

Jalal¹,

Ansari²,

Alzohairy³

et al. 2019

IJN

106

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The pathogenicity in Candida spp was attributed by several virulence factors such as production of tissue damaging extracellular enzymes, germ tube formation, hyphal morphogenesis and establishment of drug resistant biofilm. The objective of present study was to investigate the effects of silver nanoparticles (AgNPs) on growth, cell morphology and key virulence attributes of Candida species. Methods: AgNPs were synthesized by the using seed extract of Syzygium cumini (Sc), and were characterized by UV-Vis spectrophotometer, Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), and transmission electron microscopy (TEM). ScAgNPs were used to evaluate their antifungal and antibacterial activity as well as their potent inhibitory effects on germ tube and biofilm formation and extracellular enzymes viz. phospholipases, proteinases, lipases and hemolysin secreted by Candida spp. Results: The MICs values of ScAgNPs were ranged from 0.125-0.250 mg/ml, whereas the MBCs and MFCs were 0.250 and 0.500 mg/ml, respectively. ScAgNPs significantly inhibit the production of phospholipases by 82.

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“…In this context, due to the rich Brazilian biodiversity, some studies in the literature related the use of endemic plants of the country for producing AgNPs [7][8][9]. However, there are no published reports mentioning the use of Pterodon emarginatus (white sucupira) leaf extracts for this purpose.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of silver nanoparticles using aqueous extracts of Pterodon emarginatus leaves collected in the summer and winter seasons

et al. 2019

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The aim of the present study was to evaluate the potential of silver nanoparticle synthesis using extracts from the leaves of Pterodon emarginatus (white sucupira) collected during the summer and winter seasons. Leaves were collected for the production of aqueous extracts, which were added to the aqueous solutions of silver nitrate leading to a final concentration of 1 mM. The reactions were incubated at 75 °C for 150 min and monitored every 30 min by absorption spectroscopy at 425 nm. The samples were complementarily characterized by dynamic light scattering, zeta potential, transmission electron microscopy, atomic force microscopy, MALDI-TOF mass spectrometry, Fourier transform infrared spectroscopy and X-ray diffraction analyses. Both extracts (summer and winter) exhibited a satisfactory reduction of silver ions, capable of inducing the formation of AgNPPe with considerable colloidal stability. The seasons of leaf collection interfered with the synthesis and yield of the AgNPPe, and also with their hydrodynamic diameters and zeta potentials, but the particles showed similar dry sizes (height and diameter), molecular profiles, and crystallinity patterns of the atoms. In sum, the results indicated that some AgNPPe parameters can be tunable by seasonal aspects of the plants and, therefore, such nanomaterials are propitious aiming future evaluation of their applications in several areas.

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Biosynthesis of silver nanoparticles using Caesalpinia ferrea (Tul.) Martius extract: physicochemical characterization, antifungal activity and cytotoxicity

Cited by 34 publications

References 53 publications

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

<p>Anticandidal activity of biosynthesized silver nanoparticles: effect on growth, cell morphology, and key virulence attributes of Candida species</p>

Synthesis of silver nanoparticles using aqueous extracts of Pterodon emarginatus leaves collected in the summer and winter seasons

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