Biosynthesis of zinc oxide nanoparticles using aqueous extract of Andrographis alata: Characterization, optimization and assessment of their antibacterial, antioxidant, antidiabetic and anti-Alzheimer's properties

Sri, DappulaSandhya; YelamandaRao, Kandrakonda; Basha, ShaikJeelan; Lakshmi, MothukuruSree; Reddy, Lebaka Veeranjaneya; Mannarapu, Mastan; GangaiahDamu, Amooru

doi:10.1016/j.molstruc.2022.134264

Cited by 51 publications

(15 citation statements)

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“…The reported scavenging procedures of ABTS by Dappula et al [37] were applied to estimate the efficiencies of the synthetic ZnO, KNs, and ZnO/KNs materials. The ABTS solution was prepared by the complete dissolving of 44 mg of ABTS in deionized water (10 mL).…”

Section: Antioxidant Studies 241 Scavenging Of Nitric Oxide Radicalmentioning

confidence: 99%

“…This reflects enhancement by more than 42% as compared to M.ZnO, 62% as compared to KNs particles, and by about 13% as compared to the tested ascorbic acid standard (76.3 ± 1.28%) (Figure 6B). The scavenging mechanisms of the DPPH radical on the metal oxides-based antioxidants were caused by types of pair electron (e − )/proton (H + ) transfer reactions from the surfaces of these structures to the organic structures of the target DPPH radical [37,52]. The supporting of ZnO into the scrolled kaolinite nanostructure with its significant hydroxyl group, considerable photocatalytic activity, and electron-accepting/electrondonating properties can induce notably the production efficiency of the electrons on the surface of the composite (ZnO/KNs) as well as the charge separation properties which effectively induce its antioxidant potentiality [53,54].…”

Section: Dpph Radical Scavengingmentioning

confidence: 99%

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Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies

et al. 2023

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The kaolinite sheets were scrolled by sonication-induced chemical delamination processes into well-developed nanotubes (KNs) which were used as substrates for microwave-based ZnO nanoparticles (ZnO/KNs). The biological activities of synthetic ZnO/KNs structures, in terms of the antioxidant and antidiabetic properties, were assessed in comparative studies with the separated phases of the synthetic ZnO and KNs as well as the commercially used ZnO. The KNs substrate resulted in a notable enhancement in the antioxidant and antidiabetic properties of ZnO, which was assigned positive influence on the surface area, interactive interfaces, charge separation, and agglomeration properties of ZnO in addition to the detectable bioactive properties of the KNs structure. The ZnO/KNs structure achieved remarkable scavenging efficiencies for 1, 1-diphenyl-2-picrylhydrazil (DPPH) (89.8 ± 1.57%), nitric oxide (90.6 ± 1.63%), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) (86.8 ± 1.28%), and superoxide (43.9 ± 1.72%) radicals. Additionally, it shows high inhibition effects on porcine α-amylase (84.3 ± 1.92%), crude α-amylase (70.6 ± 1.37%), pancreatic α-Glucosidase (94.7 ± 1.54%), crude α-Glucosidase (95.4 ± 1.64%), and amyloglucosidase (95.3 ± 1.32%) enzymes. This antidiabetic activity is significantly higher than the activity of miglitol and close to or slightly higher than acarbose, which leads us to recommend the use of ZnO/KNs when considering the cost and side effects of the commercially used drugs.

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Section: Antioxidant Studies 241 Scavenging Of Nitric Oxide Radicalmentioning

confidence: 99%

Section: Dpph Radical Scavengingmentioning

confidence: 99%

Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies

et al. 2023

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“…The results are in agreement with others obtained for the same type of NPs synthesized with different botanical extracts. 43,44 FTIR spectroscopy Figure 5 shows FTIR spectra of ZnO NPs synthesized using the different plant extracts. All the spectra exhibit a band at 547 cm −1 assigned to the presence of ZnO NPs, 45 which supports the formation of ZnO using different botanical extracts.…”

Section: Transmission Electron Microscopymentioning

confidence: 99%

Photocatalytic activity of ZnO nanoparticles synthesized from zinc nitrate and botanical extracts of neem, chrysanthemum, Mexican marigold and shiitake mushroom

López‐Martínez

Tejeda‐Ochoa

Cervantes-Gaxiola

et al. 2023

J of Chemical Tech & Biotech

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Background Green synthesis emerges as a need to obtain functional materials, but this also involves following certain principles that imply methods and inputs that are friendlier to health and the environment. A wide variety of materials can be synthesized under these principles, one of them being ZnO, which can be used for environmental, electronic and biomedical applications to mention a few. In this work, ZnO nanoparticles (NPs) were synthesized using aqueous extracts of neem, chrysanthemum, Mexican marigold and shiitake mushroom and subsequently used to degrade methylene blue (MB) under solar light irradiation. The NPs were characterized by UV–visible spectroscopy, transmission electron microscopy, X‐ray diffraction, Fourier transform infrared spectroscopy and thermogravimetric analysis to investigate the structural, optical and electronic properties of the NPs. Results The results indicate the formation of hemispherical NPs with aggregates in a size range of 5.38–28.37 nm. All the samples presented a hexagonal wurtzite crystalline structure. The best photocatalytic performance for MB degradation was shown by ZnO NPs obtained using Mexican marigold (0.0873 ± 0.008 min−1) followed by those obtained using shiitake mushroom (0.0602 ± 0.002 min−1), neem (0.0365 ± 0.02 min−1) and chrysanthemum (0.0357 ± 0.01 min−1). Conclusions Botanical aqueous extracts have the potential to be used in the synthesis of semiconductor materials, as they allow the modification of the size and band gap. Many of the phytochemicals present in the extracts help to improve the interaction between catalyst and pollutants, in this case MB, and therefore have a positive impact on the degradation of textile pollutants. © 2022 Society of Chemical Industry (SCI).

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“…Due to their wide availability, renewability, and environmental friendliness, in addition to their immense applications in the synthesis of NPs, plant biomass is mostly targeted as a catalyst for chemical synthesis and biodiesel production [6][7][8] . Current research suggests that silver nanoparticles (AgNPs) can be used in various medical applications, including antibacterial, antifungal, anti-diabetic, anti-in ammatory, and cancer treatment, as well as diagnosis [9][10][11][12][13][14] . Silver products have long been known to have strong inhibitory and bactericidal effects and a broad spectrum of antimicrobial activities, which have been used for centuries to prevent and treat various diseases, most notably infections 15 .…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis, Characterization and Anthelmintic Activity of Silver Nanoparticles of Clerodendrum infortunatum Isolate

Majumdar

Kar

2023

Preprint

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Over the past few decades, the green synthesis of nanoparticles has gained importance for their therapeutic efficacy and eco-friendly nature. Integrating green chemistry principles into multidisciplinary nanoscience research has paved the way for developing environmentally benign and sustainable methods for synthesizing gold and silver nanoparticles. In the present study, the flowers obtained from Clerodendrum infortunatum (L.), belonging to the family Verbenaceae, have been used for biosynthesizing silver nanoparticles (AgNPs) to evaluate the anthelmintic potential. UV-Vis spectroscopy, XRD, FTIR and TEM analyses were performed to ascertain the formation of AgNPs. Clerodendrum-derived AgNP (CLE-AgNP) has significantly affected the normal physiological functions of the poultry parasite Raillietina spp., a menace to the livestock industry. Our study manifests that CLE-AgNPs cause considerable distortion of the surface tegument of this cestode parasite leading to changes in the host-parasite interface. The histochemical localization studies of the tegument-associated enzymes viz. AcPase, AlkPase, ATPase and 5’-Nu, exposed to the drug, showed a substantial activity decline, thus establishing the anthelmintic potential of the CLE-AgNPs.

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Biosynthesis of zinc oxide nanoparticles using aqueous extract of Andrographis alata: Characterization, optimization and assessment of their antibacterial, antioxidant, antidiabetic and anti-Alzheimer's properties

Cited by 51 publications

References 52 publications

Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies

Insight into the Potential Antioxidant and Antidiabetic Activities of Scrolled Kaolinite Single Sheet (KNs) and Its Composite with ZnO Nanoparticles: Synergetic Studies

Photocatalytic activity of ZnO nanoparticles synthesized from zinc nitrate and botanical extracts of neem, chrysanthemum, Mexican marigold and shiitake mushroom

Biosynthesis, Characterization and Anthelmintic Activity of Silver Nanoparticles of Clerodendrum infortunatum Isolate

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