Biotransformations by fungi

Monooxygenase-Mediated Baeyer−Villiger Oxidations

“…[166] Some Curvularia strains displayed regiodivergent biotransformations with acceptable optical purities, but significant deviation was observed among members of the same genera. [167] Similar biocatalytic activity was reported for Cylindrocarpon destructans. [168] In contrast, Cunninghamella echinulata NRRL 3655 was reported to produce the ''abnormal'' (1R,5S)-lactone 68a (30Ϫ35%, Ͼ 95% ee) exclusively, hence avoiding cumbersome chromatographic separation from the isomeric lactone.…”

Camphor-grown Pseudomonas putida, a multifunctional biocatalyst for undertaking Baeyer-Villiger monooxygenase-dependent biotransformations

“…Bicyclic lactone products were characterised and quantified by chiral capillary GC as described previously (Carnell et al, 1992).…”

Multibiorreações e suas aplicações para as sinteses de compostos enantiomericamente puros

“…ChnB2, Mycobacterium tuberculosis, entre outras), b) por fungos (Curvularia lunata, Curvularia sp., Aspergillus parasitucus, Cunninghamella echinulata, Beauveria, C. destructans Cylindrocarpon radicicola, Dreschlera, Exophiala jeanselmei, Penicillium, Mucor, Cladosporium) e c) leveduras (Geotricum candidum). 59,60,61,62,63,64,65 Infelizmente, a disponibilização destas monooxigenases não é acompanhada do conhecimento da seletividade e enantiosseletividade aos substratos. 59…”