Biphasic fish collagen scaffold for osteochondral regeneration

Biofabrication of Gingival Fibroblast Cell-Laden Collagen/Strontium-Doped Calcium Silicate 3D-Printed Bi-Layered Scaffold for Osteoporotic Periodontal Regeneration

“…In addition, collagen forms part of the extracellular matrix and thus the interactions between collagen and cells are vital in regulating cellular behaviors. Collagen has been examined as the ideal matrix to develop bi-layer scaffolds due to its outstanding biocompatibility and capacity to improve cell proliferation and differentiation, inducing several signal pathways to prove specific tissue-related protein expression [ 41 ]. Furthermore, as a natural molecule, collagen is biodegradable, biocompatible, easily available, and highly versatile, therefore making it an excellent polymer for tissue engineering [ 42 ].…”

Preparation and characterization of a novel drug-loaded Bi-layer scaffold for cartilage regeneration

“…22 Natural polymers have been extensively explored due to their structural similarity and biocompatibility with natural GAGs. [23][24][25][26][27][28][29][30] Silk is the only natural ber that exists in the form of continuous laments, and this unique advantage contributes to the diversity of silk ber applications. 31,32 The mixing of silk ber and PLA can make up for the problem of poor hydrophilicity of PLA and large brittleness at normal temperature.…”

Recent advances in 3D hydrogel culture systems for mesenchymal stem cell-based therapy and cell behavior regulation

“…62,63 Fish may be a promising alternative for collagen supply with less cost and relatively low immune response. 64 The collagen resourced from fish also handles the problem of religious limitations puzzle the use of human or mammal origin collagen. Fish collagen (FC) has been proved to possess a similar effect on facilitating early osteoblastic differentiation on human mesenchymal stem cells (hMSCs).…”