2006
DOI: 10.1016/j.colsurfb.2006.02.012
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Bis(trimethoxysilylpropyl)amine and tetraethoxysilane derived gels as effective controlled release carriers for water-soluble drugs of small molecules

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Cited by 18 publications
(17 citation statements)
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“…Organic-inorganic hybrid materials containing amine groups are desirable for various applications in catalysis, adsorption, composite materials, and drug delivery because of the chemical activity of the amines. [57][58][59][60] Materials with amines integral to the walls of the material would be especially desirable because they provide high accessibility of the amine groups. However, it is difficult to prepare ordered materials with this type of precursor.…”
Section: Full Papermentioning
confidence: 99%
“…Organic-inorganic hybrid materials containing amine groups are desirable for various applications in catalysis, adsorption, composite materials, and drug delivery because of the chemical activity of the amines. [57][58][59][60] Materials with amines integral to the walls of the material would be especially desirable because they provide high accessibility of the amine groups. However, it is difficult to prepare ordered materials with this type of precursor.…”
Section: Full Papermentioning
confidence: 99%
“…Increasing the ratio between TSPA and TEOS, for example, lowers the surface area and pore volume of the matrix, to change the diffusivity of drugs encapsulated in the matrix. [21] In contrast, quite ordered hydrophobic or oleophobic films have been derived from long-methylene-chain trialkoxysilanes like OTES, self assembled on planar surfaces, although on nano-and microparticles, the self-assembly is not preferred in solvent deposition, and the integrity of any layer formation is reported as difficult to control. [22] In the case of the capsule synthesis here, the resultant hollow capsules could be distinguished in the SEM as rigid sphere, microballon, or microcapsule ( Fig.…”
mentioning
confidence: 95%
“…Our previous works have demon- strated that the adsorption capacity of some organic dyes on hybrid gels is much higher than that on pure silica gels [3][4][5], suggesting that hydrophobic attractions between the surface organic groups of the hybrid gels and the organic dyes play an important role in adsorption. For the controlled release of dyes and drugs from hybrid gels, hydrophobic attractions were also found to play an important role [17][18][19][20]. In this study, all the gels and all the dyes have hydrophobic groups, so it is expected that hydrophobic attractions should play a role in the adsorption.…”
Section: Dye Adsorption Comparisonmentioning
confidence: 87%