2007
DOI: 10.1016/j.ajodo.2006.09.035
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Bisphosphonate treatment: An orthodontic concern calling for a proactive approach

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Cited by 73 publications
(57 citation statements)
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“…25 In addition to the above conditions related to hormonal changes, other systemic conditions have been identified that can modulate the pattern and the velocity of tooth movement: eg, diabetes, allergies, and cancer. 10 The therapeutic intake of bisphosphonates has been associated with the inhibition of tooth movement, 26 and the systemic administration of leptin, a central hormone, with the inhibition of bone formation. 27 Nonsteroidal anti-inflammatory drugs, the most common medications used in orthodontics to effectively reduce pain, can slow tooth movement by inhibiting the inflammatory reaction.…”
Section: Discussionmentioning
confidence: 99%
“…25 In addition to the above conditions related to hormonal changes, other systemic conditions have been identified that can modulate the pattern and the velocity of tooth movement: eg, diabetes, allergies, and cancer. 10 The therapeutic intake of bisphosphonates has been associated with the inhibition of tooth movement, 26 and the systemic administration of leptin, a central hormone, with the inhibition of bone formation. 27 Nonsteroidal anti-inflammatory drugs, the most common medications used in orthodontics to effectively reduce pain, can slow tooth movement by inhibiting the inflammatory reaction.…”
Section: Discussionmentioning
confidence: 99%
“…Little is known concerning orthodontic care at this point, but it is anticipated that adult orthodontic care is feasible and safe but may be slowed or even stopped during the first 3 years of oral bisphosphonate exposure due to the antiresorptive (antiosteoclastic) effects of the bisphosphonate. 38,39 Dental implant placements are also likely safe and will osseointegrate during this period. 40 However, informed consent should be provided as to an increased risk for implant failure or osteonecrosis about the implants once the oral bisphosphonate exposure exceeds 3 years.…”
Section: Preventionmentioning
confidence: 99%
“…Les auteurs admettent que la dose reçue et la durée des BP pourraient diminuer le mouvement dentaire mais ceci n'a pas été quantifié chez l'Homme [21]. Alors que certains auteurs s'accordent à dire qu'un traitement orthodontique devrait être évité chez les adultes sous BP [22,23], Krieger et al exposent, dans une récente revue de littérature, le cas d'une adolescente de 15 ans atteinte de DF de forme polyostotique, considérée à haut risque, sous 135 mg de pamidronate IV par cure depuis deux ans, ayant bénéficié avec succès d'une greffe alvéolaire pour une fente labiopalatine avec supraclusie anté-rieure. Un traitement ODF prolongé de 42 mois a été nécessaire pour obtenir une occlusion satisfaisante [24].…”
Section: Discussionunclassified