“…Based on a comparative transcriptomics analysis, we have hypothesized that a massive expansion event occurred in the class Bivalvia independently from the establishment of a large complement of C1qDC genes in the Chordates lineage (Gerdol et al, 2011). The increasing accessibility of RNA-seq datasets from non-model organisms and the recent release of the Crassostrea gigas, Pinctada fucata and M. galloprovincialis draft genomes (Nguyen et al, 2014;Takeuchi et al, 2012;Zhang et al, 2012) are leading to the explosion of bivalve-omics, making deeper investigations finally possible (Suárez-Ulloa et al, 2013). Taking advantage of the valuable oyster genome data, we have investigated the expansion of the C1qDC gene family in bivalves, their functional and structural diversification and their expression levels during development and in adult tissues.…”