Black soldier fly (Hermetia illucens) larvae meal in diets of European seabass: Effects on antioxidative capacity, non-specific immunity, transcriptomic responses, and resistance to the challenge with Vibrio alginolyticus

Effect of Feed Containing Hermetia illucens Larvae Immunized by Lactobacillus plantarum Injection on the Growth and Immunity of Rainbow Trout (Oncorhynchus mykiss)

“…However, after 6 weeks, the HIL25, HIL50, ImHIL25, and ImHIL50 groups showed similar WG compared with the HIL0 group. In the previous study, the WGs in Eurasian sea bass [21] and rainbow trout [39] fed with the feed on which part of fishmeal is replaced with HIL were similar to those of only fishmeal feed, and this is consistent with the result in the HIL group in this study. Also, in this study, at week 6 after feeding, the WG of the ImHIL group was similar to the results of the HIL and fishmeal feed groups.…”

“…Further, the RBC count and IGF-1 showed the highest value in the ImHIL50 group. Therefore, as in the previous results [19][20][21], it was confirmed that the HIL-added feed showed a better growthpromoting effect than only fishmeal-based feed, and the ImHIL feed containing a large amount of AMPs showed a better growth-promoting effect without toxicity (Figure 2). The fish liver is an important organ directly affected by food, pollutants, toxins, parasite, and microorganisms, and is also an important immunological marker because it is also involved in host defense [51].…”

“…HIL has advantages in terms of organic waste consumption, easy mass production, space-saving, and eco-friendliness [ 14 ]. HIL was reported to have a positive effect on growth when it replaces fishmeal in fish diets for species such as turbot ( Psetta maxima ), Nile tilapia ( Oreochromis niloticus ), mirror carp ( Cyprinus carpio ), yellow catfish ( Pelteobagrus fulvidraco ), rainbow trout ( Oncorhynchus mykiss ), Eurasian perch ( Perch fluviatilis ), and European seabass ( Dicentrachus labrax ) [ 10 , 11 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ]. HIL-containing fish feed downregulates the expression of inflammatory factors such as toll-like receptor 22 (TLR22), CCAAT-enhancer-binding protein (C/EBPβ), mitogen-activated phosphokinase p38 (p38 MAPK), lipoxygenase-5 (LOX5), and oxidative stress-related genes, such as glutathione peroxidase enzyme (Gpx1), copper/zinc-superoxide dismutase (Cu/Zn-SOD), and manganese superoxide dismutase (Mn-SOD) [ 2 ].…”

“…However, AMP, a natural antibacterial agent derived from organisms, is safe in the environment and body [ 22 ]. Recently, a study on the effect of rainbow trout diets containing HIL on growth performance, feed efficiency, nutrient deposition, blood glucose, lipid digestibility, and sensory profile was conducted [ 17 , 18 , 19 , 20 , 21 ]. Similarly, studies were conducted on effects on broiler growth performance, feed choice, blood traits, carcass characteristics, and meat quality [ 14 , 29 ].…”

Growth of Yellowtail (Seriola quinqueradiata) Fed on a Diet Including Partially or Completely Defatted Black Soldier Fly (Hermetia illucens) Larvae Meal

“…BSF larvae offer more than just a protein source. A novel bioactive polysaccharide that can stimulate innate immunity was identified in BSF larvae [6], while dietary BSF larvae were reported to provide improvements in immunity and disease resistance in barramundi (Lates calcarifer) [7] and European seabass (Dicentrarchus labrax) [8].…”