Bladder cancer and the aluminium industry: a review

Guzzo, Thomas J.; Bivalacqua, Trinity J.; Schoenberg, Mark

doi:10.1111/j.1464-410x.2008.07903.x

Cited by 5 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Relative risk increases in proportion to the time worked (RR = 1.2:1 year; 1.9:1–9 years; 3.0:10–19 years; 3.2:20–29 years and 4.5:≥30 years of job experience). 33 …”

Section: Occupational Factors4510112127–40mentioning

confidence: 99%

Factores de riesgo constitucionales y ocupacionales asociados al cáncer vesical

Ferrís

García

Berbel

et al. 2013

Actas Urológicas Españolas

View full text Add to dashboard Cite

Objective Bladder carcinoma (BC) is the fourth most common type of cancer in males from Western countries, with primary prevention an important healthcare challenge. We review the associated constitutional and occupational risk factors (RF), with greater or lesser scientific evidence, in the etiology of BC. Material and methods Literature review of the last 25 years of the constitutional and occupational RF associated with BC, conducted on MedLine, CancerLit, Science Citation Index and Embase. The search profiles were Risk factors/Genetic factors/Genetic polymorphisms/Epidemiology/Occupational factors and Bladder cancer. Results The main RF were (a) age and gender (diagnosed at age 65 and over, with a 4:1 ratio of males to females); (b) race, ethnicity and geographic location (predominantly in Caucasians and in Southern European countries); (c) genetic (N-acetyltransferase-2 and glutathione s-transferase M1 gene mutations, which significantly increase the risk for BC); (d) occupational, which represent 5–10% of BC RF; and (f) occupations with high BC risk, such as aluminum production, the manufacture of dyes, paints and colourings, the rubber industry and the extraction and industrial use of fossil fuels. Conclusions BC is the end result of the variable combination of constitutional and environmental RF, the majority of which are unknown. The most significant constitutional RF are related to age, gender, race, ethnicity geographic location and genetic polymorphisms. The main occupational RF are those related to aromatic amines and polycyclic aromatic hydrocarbons.

show abstract

“…Relative risk increases in proportion to the time worked (RR = 1.2:1 year; 1.9:1–9 years; 3.0:10–19 years; 3.2:20–29 years and 4.5:≥30 years of job experience). 33 …”

Section: Occupational Factors4510112127–40mentioning

confidence: 99%