Bladder Cancer Risk in Painters: a Review of the Epidemiological Evidence, 1989–2004*

Bosetti, Cristina; Pira, Enrico; Vecchia, Carlo La

doi:10.1007/s10552-005-3636-5

Cited by 29 publications

(21 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Occupational exposure to aromatic amines has long been recognized a risk factor for bladder cancer (Negri et al, 1989;Kogevinas et al, 2003;Bosetti et al, 2005;Pira et al, 2010;Pira et al, 2012), accounting for up to 15% of cases in men from selected high-risk populations D'Avanzo et al, 1995). However, a selected number of occupations a priori deemed as being of high risk for bladder cancer showed only a moderate, nonsignificant excess risk, indicating that occupational exposures are not a major factor for bladder cancer in this, mainly rural, population.…”

Section: Discussionmentioning

confidence: 99%

Smoking, occupation, history of selected diseases and bladder cancer risk in Manisa, Turkey

Erdurak

Dündar

Özyurt

et al. 2014

European Journal of Cancer Prevention

View full text Add to dashboard Cite

The aim of the study was to identify and quantify the reasons for the high bladder cancer rates in Turkey. We conducted a case-control study in Manisa, Turkey, in 2011. The study included 173 patients with incident, histologically confirmed bladder cancer and 282 controls who were frequency matched by age, sex and geographic area, admitted to the main hospital of Manisa for a wide range of acute diseases. Adjusted odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) were derived from multiple logistic regression models. Compared with never smokers, the OR was 2.9 (95% CI 1.5-5.4) for moderate (<20 cigarettes/day) and 4.0 (95% CI 1.7-9.6) for heavy smokers. The association was stronger for unfiltered black tobacco (OR=5.4) and for longer duration of smoking (≥40 years, OR=5.3). There was a strong inverse correlation with social class indicators, with ORs of 0.2 (95% CI 0.1-0.4) for more-educated compared with less-educated individuals. There was no significant association with a group of five occupations a priori defined as being of high risk (OR=1.3), nor with farming (OR=1.2). Bladder cancer risk was directly related to the history of urinary tract infections (OR=1.9, 95% CI 1.2-3.1) but not to diabetes (OR=0.7) or kidney (OR=0.7) and prostate (OR=1.3) diseases. Tobacco is the major risk factor for bladder cancer in Manisa, being responsible for 56% of cases; urinary tract infections account for 19% of cases, whereas the role of occupational exposure is limited in this, predominantly rural, population.

show abstract

Section: Discussionmentioning

confidence: 99%

Smoking, occupation, history of selected diseases and bladder cancer risk in Manisa, Turkey

Erdurak

Dündar

Özyurt

et al. 2014

European Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…They restricted their analysis to cohort studies that reported a standardized mortality ratio (SMR) or relative risk (RR) based on person-time at risk and included observed numbers of death or confidence intervals (CIs). In a more recent meta-analysis of cancer risk in painters, Bosetti et al (2005) identified both cohort and case-control studies published between 1989 and 2004; however, the meta-analysis only considered bladder cancer.…”

Section: Introductionmentioning

confidence: 99%

Meta-analyses of occupational exposure as a painter and lung and bladder cancer morbidity and mortality 1950–2008

Bachand

Mundt

et al. 2010

Critical Reviews in Toxicology

View full text Add to dashboard Cite

The International Agency for Research on Cancer (IARC) classified occupational painting as a human carcinogen based on lung and bladder cancers; however, no specific exposures were implicated. The authors conducted comprehensive meta-analyses of the epidemiological literature on occupational painting and these cancers. The authors abstracted study results and confounder information, and used quantile plots and regression models to evaluate heterogeneity and publication bias. Summary risk estimates were derived and sensitivity analyses performed to evaluate smoking, socioeconomic status (SES), and exposure variables. Where applicable, a Bayesian approach was used to externally adjust for smoking, a major risk factor for both cancers. For lung cancer cohort mortality studies, publication bias and heterogeneity were seen, and earlier studies reported higher risk estimates than later studies. Overall lung cancer summary risk estimates were 1.29 for case-control and 1.22 and 1.36 for cohort morbidity and mortality studies, respectively, and risk estimates for bladder cancer were 1.28 for case-control and 1.14 and 1.27 for cohort morbidity and mortality studies, respectively (all statistically significant). Risks did not differ between painters and mixed occupations. Nonsignificant summary estimates resulted for lung and bladder cancers when controlling for SES, or externally adjusting for smoking in lung cancer studies. Summary risks varied by control source for case-control studies. Residual confounding by smoking and SES, lack of exposure group effect, and publication bias limit the ability of the meta-analyses to explain associations observed between occupational painting and lung and bladder cancers. Given the long latencies for lung and bladder cancers, these weak associations, if real, may not be elucidated through studies of occupational painting today.

show abstract

“…Five meta-analyses have demonstrated a significant or borderline significant increased incidence of or mortality from bladder cancer among persons occupationally exposed as a painter (Bachand et al, 2010a,b;Bosetti et al, 2005;Chen and Seaton, 1998;Guha et al, 2010;Yamaguchi et al, 1991).…”

Section: Rubber Industrymentioning

confidence: 99%

Occupational Carcinogenesis☆

Rushton¹

2014

Reference Module in Biomedical Sciences

View full text Add to dashboard Cite

Bladder Cancer Risk in Painters: a Review of the Epidemiological Evidence, 1989–2004*

Cited by 29 publications

References 28 publications

Smoking, occupation, history of selected diseases and bladder cancer risk in Manisa, Turkey

Smoking, occupation, history of selected diseases and bladder cancer risk in Manisa, Turkey

Meta-analyses of occupational exposure as a painter and lung and bladder cancer morbidity and mortality 1950–2008

Occupational Carcinogenesis☆

Contact Info

Product

Resources

About