Bleached smear microscopy provides higher yield in diagnosing pulmonary tuberculosis

Kandati, Jithendra; Boorsu, Suresh Kumar; Pathalapati, Ramamohan; Buchineni, Madhavulu

doi:10.18203/2320-6012.ijrms20161784

Cited by 1 publication

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“…In the current study, the incidence of pulmonary TB was found to be 45%, this is comparable to study conducted by Singh et al which had an incidence of 51%, whereas few other studies done by Patel et al and Ahmed et al, the incidences were 86% and 80% respectively. 13,15,16 Amongst the cases of pulmonary TB, sputum positivity for AFB was seen in 14% of patients, whereas in study done by Patel et al, it was found to be 25.8%, and study by Ahmed et al, its 37%, the probable reason for less sputum positivity in the current study could be because of low mean CD4 count. 15,16 The situation in HIV uninfected tuberculosis patients is very different from this and indicates sputum smear is not a sensitive diagnostic tool in the presence of HIV infection.…”

Section: Resultscontrasting

confidence: 62%

Clinical and laboratory profile of tuberculosis in HIV positive individuals

B.¹,

Bhandarkar

Nandalike³

et al. 2022

Int J Res Med Sci

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Background: Tuberculosis (TB), major public health problem in most of the developing countries. There is significant difference in the laboratory profile of tuberculosis in human immuno-deficiency virus (HIV) infected compared to immunocompetent host. Prompt diagnosis and treatment of tuberculosis in HIV infected will improve the morbidity and mortality associated with dual infection. Objectives of the research were: to study about the clinical profile of tuberculosis in HIV positive individuals; and also, to study about the laboratory profile of tuberculosis in HIV positive individuals.Methods: Patients with HIV positive status who fulfill the inclusion and exclusion criteria and admitted in Adichunchanagiri hospital and research center, BG Nagara Mandya district, Karnataka India, during the period of January 2020 to June 2021.Results: Fever was the most common symptom (92.8%). Most common manifestation was extrapulmonary TB (54%). TB meningitis was the most common extra pulmonary involvement seen in 28.67%. Amongst patients with pulmonary TB, 6.3% of cases were smear positive for AFB bacilli, 58% of cases had pulmonary infiltrates on chest X-ray. In all cases of extra pulmonary TB (EPTB) CD4T cell counts were <200 cells/μl.Conclusions: Chest X-rays were atypical with more of lowerzone infiltrative lesions. Sputum acid-fast bacillus (AFB) is negative in most of the patients with pulmonary TB, however had sputum cartridge based nucleic acid amplification test (CBNAAT) positive status, hence sputum CBNAAT remains the gold standard investigation. Fluid analysis with ADA correlation holds good for the diagnosis of TB meningitis and tubercular pleural effusion.

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Section: Resultscontrasting

confidence: 62%