Blended Gels of Sodium Carboxymethyl Cellulose Incorporating Antimicrobials for Absorbance and Wound Healing Applications

Oliveira, Renata Nunes; McGuinness, Garrett B.

doi:10.1007/978-3-319-76573-0_39-1

Cited by 2 publications

(3 citation statements)

References 130 publications

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“… 91 The addition of PVA to the base mixture can form a stronger and relatively rigid hydrogel through physical crosslinking processes. 92 Hydrogels containing NaCMC have significant potential to meet the requirements of effective wound care dressings, especially when mixed with natural antimicrobials. 92 The addition of pectin-cellulose can provide a more stable hydrogel with good biocompatibility and haemostatic ability.…”

Section: Alginate and Chitosan-based Hydrogel Application For Topical...mentioning

confidence: 99%

“… 92 Hydrogels containing NaCMC have significant potential to meet the requirements of effective wound care dressings, especially when mixed with natural antimicrobials. 92 The addition of pectin-cellulose can provide a more stable hydrogel with good biocompatibility and haemostatic ability. 93 Additionally, the use of other decorative polymers such as sodium glycerophosphate and Pluronic acid is generally employed to obtain pH or temperature-sensitive release characteristics.…”

Section: Alginate and Chitosan-based Hydrogel Application For Topical...mentioning

confidence: 99%

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Alginate and Chitosan-Based Hydrogel Enhance Antibacterial Agent Activity on Topical Application

Wathoni,

Suhandi,

Ghassani Purnama

et al. 2024

IDR

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Untreated topical infections can become chronic, posing serious health issues. Optimal skin adherence is crucial in addressing such infections. In this context, chitosan and alginate emerge as promising candidates for use as a foundation in the development of topical hydrogels. The aim of this review is to examine the literature on topical hydrogel formulations that use chitosan and alginate as foundations, specifically in the context of topical antibacterial agents. The research methodology involves a literature review by examining articles published in databases such as PubMed, Scopus, ScienceDirect, and Google Scholar. The keywords employed during the research were “Alginate”, “Chitosan”, “Hydrogel”, and “Antibacterial”. Chitosan and alginate serve as bases in topical hydrogels to deliver various active ingredients, particularly antibacterial agents, as indicated by the search results. Both have demonstrated significant antibacterial effectiveness, as evidenced by a reduction in bacterial colony counts and an increase in inhibition zones. This strongly supports the idea that chitosan and alginate could be used together to make topical hydrogels that kill bacteria that work well. In conclusion, chitosan and alginate-based hydrogels show great potential in treating bacterial infections on the skin surface. The incorporation of chitosan and alginate into hydrogel formulations aids in retaining antibacterial agents, allowing for their gradual release over an optimal period. Therefore, hydrogels specifically formulated with chitosan and alginate have the potential to serve as a solution to address challenges in the treatment of topical bacterial infections.

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Section: Alginate and Chitosan-based Hydrogel Application For Topical...mentioning

confidence: 99%

Section: Alginate and Chitosan-based Hydrogel Application For Topical...mentioning

confidence: 99%

Alginate and Chitosan-Based Hydrogel Enhance Antibacterial Agent Activity on Topical Application

Wathoni,

Suhandi,

Ghassani Purnama

et al. 2024

IDR

View full text Add to dashboard Cite

show abstract

“…Propolis extract, which is a resinous blend produced by bees, also exhibits properties that counteract bacteria, fungi, viruses, oxidation, and inflammation. These effects stem from a diverse array of chemical constituents present, including aglycone flavonoids, phenolic acids, and ester derivatives [ 175 , 176 ]. Aloe vera and chitosan are additional instances of natural sources featuring antimicrobial attributes due to their chemical makeup.…”

Section: Bioactive Moleculesmentioning

confidence: 99%

Natural and Synthetic Polymeric Biomaterials for Application in Wound Management

Prete,

Dattilo,

Patitucci

et al. 2023

JFB

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Biomaterials are at the forefront of the future, finding a variety of applications in the biomedical field, especially in wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try to heal through a series of interconnected processes involving several initiators and mediators such as cytokines, macrophages, and fibroblasts. The combination of biopolymers with wound healing properties may provide opportunities to synthesize matrices that stimulate and trigger target cell responses crucial to the healing process. This review outlines the optimal management and care required for wound treatment with a special focus on biopolymers, drug-delivery systems, and nanotechnologies used for enhanced wound healing applications. Researchers have utilized a range of techniques to produce wound dressings, leading to products with different characteristics. Each method comes with its unique strengths and limitations, which are important to consider. The future trajectory in wound dressing advancement should prioritize economical and eco-friendly methodologies, along with improving the efficacy of constituent materials. The aim of this work is to give researchers the possibility to evaluate the proper materials for wound dressing preparation and to better understand the optimal synthesis conditions as well as the most effective bioactive molecules to load.

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Blended Gels of Sodium Carboxymethyl Cellulose Incorporating Antimicrobials for Absorbance and Wound Healing Applications

Cited by 2 publications

References 130 publications

Alginate and Chitosan-Based Hydrogel Enhance Antibacterial Agent Activity on Topical Application

Alginate and Chitosan-Based Hydrogel Enhance Antibacterial Agent Activity on Topical Application

Natural and Synthetic Polymeric Biomaterials for Application in Wound Management

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