Blood and Body Fluid Exposures in Health-Care Settings: Risk Reduction Practices and Postexposure Prophylaxis for Health-Care Workers

Narin, Inci; Gedık, Habip; Voß, Andreas

doi:10.1007/s11908-012-0297-x

Cited by 3 publications

(2 citation statements)

References 21 publications

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“…In accordance with other authors, we found that factors associated with decreased immunogenicity were older age, sex and obesity, while we did not find Testing HCP as well as medical and dental students for anti-HBs levels may be warranted, as these categories of workers represent a high-risk population: indeed, there are approximately 66,000 HBV infections per year worldwide [20] [21] [22]. This is particularly relevant in countries such as Italy where there is no post-vaccination serological testing, making it impossible to identify unvaccinated subjects [23] [24].…”

Section: Discussionsupporting

confidence: 90%

Seropositivity for Hepatitis B Virus, Vaccination Status and Response to Vaccine in a Cohort of Dental Students

Lamberti¹,

Garzillo²,

Muoio³

et al. 2017

OJPM

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Background: The development of a vaccine against hepatitis B virus (HBV) has been a major achievement in terms of prevention of HBV infection. To evaluate the immunological status against HBV of dental-profession students, we analysed the long-term immunogenicity and effectiveness of HBV vaccination in Italian dental students with different work seniorities, determining the influence of epidemiological variables on the immune response. Methods: This study, carried out from January 2014 to April 2016, involved 361 underand post-graduate dental students attending the Second University of Naples. HBV serum markers were determined and multivariate logistic regression analysis was used to identify factors associated with the level of long-term immunogenicity. Results: Of the 361 subjects evaluated, 15 (4.2%) declared no history of vaccination. All vaccinated subjects were HBsAg/anti-HBc negative, with 86 (24.9%) having an anti-HBs titre <10 IU/L. The latter were younger, more likely to be attending undergraduate dental school, and more likely to have been vaccinated in infancy. Conclusion: The findings of this study suggest that assessment of HBV serum markers in workers potentially exposed to hospital infections is useful to identify small numbers of unvaccinated subjects or vaccinated subjects with low antibody titre, all of whom should be referred for a booster series of vaccinations.

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Section: Discussionsupporting

confidence: 90%

Seropositivity for Hepatitis B Virus, Vaccination Status and Response to Vaccine in a Cohort of Dental Students

Lamberti¹,

Garzillo²,

Muoio³

et al. 2017

OJPM

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“…Even though other microorganisms may cause bloodborne diseases, "hepatitis B, C, and human immunodeficiency virus" are the most common pathogens [20]. Insecure injection practices are a significant public health problem and can direct the transmission of bloodborne pathogens [21].…”

Section: Introductionmentioning

confidence: 99%

Hepatitis B, C, and HIV Infections among blood Donors at Several Hospitals in Lahore, Pakistan

Arshad

Arif

Ahmad³

et al. 2021

JPRI

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The study's objectives are to find out the frequency of hepatitis C, B, and HIV infection among blood donors at different hospitals of Lahore; to understand the relationship of demographic risk factors contributing to the positive cases of hepatitis C, B, and HIV. A cross-sectional study with random sampling in which 200 blood donors participated. A questionnaire was used to record the social and personal practices. A small percentage of blood donors have a history of jaundice. More than one-fourth had undergone surgical intervention, and more than one-third had suffered a needle stick injury. The vast majority had a history of I/V injections/drips, tooth extraction/dental operations, or both. 10.5% of blood donors were Anti-HBV positive, 12.5% were Anti-HCV positive, and 0.5% were HIV positive. Shaving from community barbers should be avoided. In addition, to overcome hepatitis B, C, and HIV transmission, health education programs should be held among blood donors and the general public to prevent them from infection.

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Vaccination against hepatitis b virus: are Italian medical students sufficiently protected after the public vaccination programme?

Lamberti

Rosa

Garzillo

et al. 2015

J Occup Med Toxicol

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BackgroundThe development of a vaccine against hepatitis B virus (HBV) has been a major achievement in terms of prevention of HBV infection. For the present study, we analysed the long-term immunogenicity and effectiveness of HBV vaccination among healthcare students with different working seniorities.MethodsA cross-sectional study of undergraduate and postgraduate students attending the Medical School of the Second University of Naples was conducted between September 2012 and December 2014. HBV serum markers were determined and multivariate logistic regression analysis was used to identify factors associated with the level of long-term immunogenicity.ResultsOf the 2,932 subjects evaluated, only 33 (1.1 %) declared no history of vaccination. All vaccinated subjects were HBsAg/anti-HBc negative, 459 of which had an anti-HBs titre <10 IU/L. The latter were younger, more likely to be attending a healthcare profession school (i.e., dental hygienists, nursing, paediatric nursing, radiography and midwifery) than a medical school (at either undergraduate or postgraduate level) and more likely to have been vaccinated in infancy.ConclusionThe results of this study suggest that assessment of HBV serum markers in workers potentially exposed to hospital infections is useful to identify small numbers of unvaccinated subjects or vaccinated subjects with low antibody titre, all of whom should be referred to a booster series of vaccinations.

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Blood and Body Fluid Exposures in Health-Care Settings: Risk Reduction Practices and Postexposure Prophylaxis for Health-Care Workers

Cited by 3 publications

References 21 publications

Seropositivity for Hepatitis B Virus, Vaccination Status and Response to Vaccine in a Cohort of Dental Students

Seropositivity for Hepatitis B Virus, Vaccination Status and Response to Vaccine in a Cohort of Dental Students

Hepatitis B, C, and HIV Infections among blood Donors at Several Hospitals in Lahore, Pakistan

Vaccination against hepatitis b virus: are Italian medical students sufficiently protected after the public vaccination programme?

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