“…There are controversies as to wheth er Cd causes hypertension either clinically or experimentally. There is evidence for [Schroeder, 1965;Mackenzie and Kay, 1973;Glauser et al, 1976] and against [Beevers et al, 1976;Ostergaard, 1977;Dally et al, 1978] as far as clinical reports are concerned. When Cd is fed to rats orally, both positive [Schroeder and Buckman, 1967;Kanisawa and Schroeder, 1969;Perry et al, 1977Perry et al, , 1979Petering et al, 1979;Fadloun and Leach, 1980] and negative [Lener and Bibr, 1971;Doyle et al, 1975;Eakin et al, 1980] pressure effects have been reported.…”