Blood Cholesterol Studies in Biliary and Hepatic Disease

The Lipids of Serum and Liver in Patients With Hepatic Diseases 1

“…Neutral fat is, however, high in biliary obstruction and in infectious hepatitis, as compared with cirrhosis and toxic hepatitis in which it is usually comparatively low. From Figures 4 and 5, it will be seen that in both biliary obstruction and in some cases of infectious hepatitis neutral fat rises, to fall again as the obstruction is relieved or the icterus sub- The interrelationships of the serum lipids It has been reported repeatedly that the ratio of free to total cholesterol is frequently elevated in hepatic disease (8,9). Published data have, however, been obtained almost entirely by colorimetric procedures that yield higher and more variable ratios than does the digitonin method employed for the present study.…”

Clinical Significance of the Cholesterol Partition of the Blood Plasma in Hepatic and in Biliary Diseases

“…An explanation for the absence of hypercholesterolemia in these 23 cases cannot be given. However, in cases 15,17,21,42,74,75,96 and 103 there was only one determination of the blood cholesterol, and it is conceivable that the later level might have been higher. In cases 15,98,99 and 105 the degree of obstruction was slight, and the level of the blood cholesterol was correspondingly not high.…”

“…However, in cases 15,17,21,42,74,75,96 and 103 there was only one determination of the blood cholesterol, and it is conceivable that the later level might have been higher. In cases 15,98,99 and 105 the degree of obstruction was slight, and the level of the blood cholesterol was correspondingly not high. In cases 21, 42, 86, 89, 90, 97 Of the 26 instances of obstructive jaundice in which the blood cholesterol ester was below 150 mg. in 100 cc, the ester remained normal or slightly raised in 18.…”

Evaluation of Drugs Commonly Employed as Diagnostic Aids in Clinical Medicine

“…The two most commonly used dyes, rose bengal and bromsulphalein, when retained in the blood plasma, may be visualized and measured quantitatively by colorimetric methods. The 5 technic of the rose bengal test was described in 1924 u and, as first proposed, the degree of excretion of the dye was estimated by colorimetric readings. Althausen,Biskind and Kerr 12 recently have shown that the test could be more sensitive and the limits of the test 5 per cent lower by using the spectroscope instead of the colorimeter.…”