2020
DOI: 10.1111/bjh.17007
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Blood component use in critical care in patients with COVID‐19 infection: a single‐centre experience

Abstract: Summary There has been a significant surge in admissions to critical care during the coronavirus disease 2019 (COVID‐19) pandemic. At present, the demands on blood components have not been described. We reviewed their use during the first 6 weeks of the outbreak from 3 March 2020 in a tertiary‐level critical care department providing venovenous extracorporeal membrane oxygenation (vv‐ECMO). A total of 265 patients were reviewed, with 235 not requiring ECMO and 30 requiring vv‐ECMO. In total, 50 patients requir… Show more

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Cited by 18 publications
(19 citation statements)
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“…ECMO related anemia and coagulopathy led to 100% blood transfusion in our ECMO group to maintain hemoglobin levels above 70 g/L and relatively normal coagulation parameters. We noticed that red cell concentrates were the most frequently transfused component in COVID-19 patients on ECMO, which was also reported by other teams [26,27]. Fresh frozen plasma, cryoprecipitate and platelet transfusions were used to balance the coagulation system.…”
Section: Discussionsupporting
confidence: 71%
“…ECMO related anemia and coagulopathy led to 100% blood transfusion in our ECMO group to maintain hemoglobin levels above 70 g/L and relatively normal coagulation parameters. We noticed that red cell concentrates were the most frequently transfused component in COVID-19 patients on ECMO, which was also reported by other teams [26,27]. Fresh frozen plasma, cryoprecipitate and platelet transfusions were used to balance the coagulation system.…”
Section: Discussionsupporting
confidence: 71%
“…Less than 20% of patients with COVID-19 received blood transfusions. [19][20][21] The details of ABO matching can easily be reported, 22 as they are routinely known. When properly documented, the combined data from small prospective observational studies can amount to impressive case series.…”
mentioning
confidence: 99%
“…Which comorbidities are predisposing to blood transfusion and severity of viral disease? This short report from critical care at a large academic centre in London, UK 6 may not be representative of general clinical settings in primary care hospitals. Hence, more such descriptions of transfusion requirements could be informative, which will eventually allow us to compare the practice among patient cohorts in different countries.…”
mentioning
confidence: 94%
“…For the patients who did require transfusion, the component types and clinical indications remained to be discerned. In this issue, Doyle et al 6 . describe transfusion practice for patients with COVID‐19 in intensive care units (ICUs), some requiring extracorporeal membrane oxygenation (ECMO), as one of the first reports on this topic.…”
mentioning
confidence: 99%
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