Blood Donors and Their Deferral Pattern in a University Hospital, Nepal

Koju, Surendra; Bhatt, RajendraDev; Shankhadev, Ramita; Twitwi, Rosna

doi:10.4103/gjtm.gjtm_11_22

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…(95.6% vs 4.4%). This was similar to many other studies done by Anegundi et al [11] (83.3%), Shah et al [21] (87.6%) Koju et al [20] (92.6%). This denotes that most of the donors can be recruited back to the donor pool with proper counselling and management.…”

Section: Discussionsupporting

confidence: 91%

“…Hypertension was the major cause of donor deferral in this study (20.2%). Many other studies have also shown Hypertension as the major cause of deferral [11,12,20,22]. Hypertension was seen to be cause of permanent deferral in previous studies.…”

Section: Discussionmentioning

confidence: 73%

“…Author Name Study period Deferral rate (%) Shastry et al [15] 13 years 5.6% Sundar et al [16] 3 years 6% Shrivastava et al [1] 12 years 11.5% Agnihotri [17] 1.5 years 11.6% R K Chaudary et al [9] 2 years 16.4% Bahadur et al [6] 2 years 9% Anegundi R. et al [11] 1 year 13.6% Haque et al [18] 6 months 20% H Gulen et al [19] 6 months 27.6% Koju et al [20] 4 years 9.5% Present study 4.5 years 19.1%…”

Section: Table 5 Comparison Of Donor Deferral Percentage In Various S...mentioning

confidence: 99%

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Profile of Blood Donors and Deferral Reasons in a Tertiary Care Centre in South India

Rajan

Anu

Mathew

2022

JAMMR

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Aim: To assess the demographic profile of blood donors and determine the frequency and causes for deferral. Study Design: Retrospective cross-sectional study. Place and Duration of Study: Department of Pathology, Blood Centre at Dr. SMCSI medical college, Karakonam, Trivandrum. January 2018 to September 2022. Methodology: This study was done to analyze the various causes of deferral and the profile of donors. 8064 donors from the study period were analyzed and their demographic profile was recorded. The deferred donors were analyzed according to their age, sex, type of donor, type of deferral and reasons for deferral. Results: 8064 donors came to our center for donation of which 7682 (95.3%) were males and 382 (4.7%) were females. Majority of blood donors belonged to age group 18-25 years (50.6%). Replacement donors accounted for 6596 donors (81.8%). Voluntary donors were only 940 (11.7%). 1541 (19.1%) donors were deferred from donating. Out of these, 1186(77%) were replacement donors, 198(12.8%) were voluntary donors and 160(10.2%) were family donors. The most frequent causes of temporary deferrals: Hypertension 314(20.2%), Hypotension 82(5.3%), low hemoglobin 110(7.1%), On medication 104(6.7%), Tattoo/ ear piercing/smoking/pan chewing 154(10%), previous recent illness/surgery 190(12.3%) and alcoholism 46(3%). Permanent deferrals were done for only 68 donors (0.7%). They included 21 high risk donors and 47 donors who were serology positive. Conclusion: Deferral pattern analysis can help the medical personnel in knowing the common causes of deferral and be more focused in screening. Determination of cause and rate donor deferral can help in preventing loss of precious blood and components.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 73%

Section: Table 5 Comparison Of Donor Deferral Percentage In Various S...mentioning

confidence: 99%

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Profile of Blood Donors and Deferral Reasons in a Tertiary Care Centre in South India

Rajan

Anu

Mathew

2022

JAMMR

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Self-reported high-risk behavior among first-time and repeat replacement blood donors; a four-year retrospective study of patterns

Osei-Boakye,

Nkansah,

Appiah

et al. 2024

PLoS ONE

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Background There is no replacement for blood, and patients requiring transfusion depend on human donors, most of whom are family donors. Family donors may deny engagement in high-risk activities, which threaten the safety of donated blood. This study determined frequency of self-reported high-risk behaviors among replacement donors. Methods This retrospective study recruited 1317 donor records from 2017–2020, at Mankranso Hospital, Ghana. Data from archived donor questionnaires were extracted and analyzed with SPSS and GraphPad. Frequencies, associations, and quartiles were presented. Results The donors were predominantly males (84.4%), 17–26 years old (43.7%), informal workers (71.8%), rural inhabitants (56.5%), first-time (65.0%), and screened in the rainy season (56.3%). Donation frequency was significantly associated with age, sex, occupation, and residence. Repeat donors were significantly older (p≤0.001). More males than females were deferred (p = 0.008), drug addicts (p = 0.001), had body modifications (p = 0.025), multiple sexual partners (p = 0.045), and STIs (p≤0.001), whereas, more females were recently treated (p = 0.044). Weight loss (p = 0.005) and pregnancy (p = 0.026) were frequent among 17–26-year group, whereas, tuberculosis was frequent among 37–60-year group (p = 0.009). More first-time donors were unwell (p = 0.005), deferred (p≤0.001), pregnant (p = 0.002), drug addicts, had impending rigorous activity (p = 0.037), body modifications (p = 0.001), multiple sexual partners (p = 0.030), and STIs (p = 0.008). STIs were frequent in the dry season (p = 0.010). First-time donors had reduced hemoglobin (p = 0.0032), weight (p = 0.0003), and diastolic pressure (p = 0.0241). Conclusion Donation frequency was associated with age, sex, occupation, and residence, with first-time donors younger than repeat donors. Deferral from donation, drug addiction, body modification, multiple sexual partners, and STIs were frequent among males, whereas, more females received treatment. Tuberculosis was frequently reported among older adults, whereas, weight loss and pregnancy were frequent among younger individuals. More first-time donors reported being unwell, deferred, drug addiction, body modifications, multiple sexual partners, STIs, and pregnant. Hemoglobin, weight, and diastolic BP were reduced among first-time donors.

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Analysis of Causes for Pre-Donation Deferral Among Voluntary Blood Donors at a Tertiary Care Hospital

SA,

et al. 2023

Asian J Pharm Clin Res

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Objectives: Pre-donation screening of potential blood donors is critical for ensuring the safety of the blood collected, and donor deferral as a result of risk factors is practiced worldwide. It is important to study the pattern of deferrals to reduce unnecessary deferrals and encourage continuous blood donation. The aim of the present study was to determine the rate and reasons for pre-donation donor deferral among voluntary blood donors. Methods: This was a single-center, retrospective cross-sectional study conducted by analyzing 3 years of data, from January 2020 to December 2022, over a period of 2 months (December 2022 and January 2023) retrieved from the donor deferral register. The data was entered in Microsoft Excel and analyzed using the Statistical Package for the Social Sciences software. Descriptive statistical measures were utilized to present the data. Results: Among 29,847 voluntary donors, 13.81% (4123/29,847) were deferred, of whom 84.2% (3472/4123) were males. The deferral rate among males was 12.19% (3472/28,480), while it was 47.62% (651/1367) in females. 53.04% of the deferred donors were in the age group of 18–30 years (2187/4123). 98.73% (4071/4123) of the deferrals were temporary. Hypothyroidism on treatment (42.30%, 22/52), uncontrolled diabetes on insulin (34.62%, 18/52), and epilepsy on treatment (11.54%, 6/52) were the common reasons for permanent deferral, while low hemoglobin (13.07%, 532/4,123), medications (11.67%, 475/4,071), and body piercing (9.85%, 406/4,123) were the most common reasons for temporary deferral. Low hemoglobin was the common reason for deferral among repeat donors (55.45%, 295/532) compared to first-time donors. Conclusion: The current findings suggest that it is important to increase awareness of voluntary, non-remunerated blood donation among young people and educate people about the common criteria for a healthy donor to minimize the loss of blood donors.

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Blood Donors and Their Deferral Pattern in a University Hospital, Nepal

Cited by 4 publications

References 12 publications

Profile of Blood Donors and Deferral Reasons in a Tertiary Care Centre in South India

Profile of Blood Donors and Deferral Reasons in a Tertiary Care Centre in South India

Self-reported high-risk behavior among first-time and repeat replacement blood donors; a four-year retrospective study of patterns

Analysis of Causes for Pre-Donation Deferral Among Voluntary Blood Donors at a Tertiary Care Hospital

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