“…These three parameters have been examined in many ways: in animals, for example, by histology, tissue pressure measurements, isotope clearance, radiolabelled microspheres and photoplethysmography. For obvious reasons, investigations on human teeth tend to be rather more restricted, with post-extraction histology providing the majority of information; this has been reviewed by Tonder (1980). Until very recently direct, non-Correspondence: Petra E. E. B. Wilder-Smith, Klinik fiir Mund-, Zahn-und Kieferkrankheiten der Universitat Heidelberg, Poliklinik fiir Zahnerhaltungskunde, Im Neuenheimer Feld 400, D-6900 Heidelberg, W. Germany.…”