Blood gastrin and pepsinogen responses to subclinical infection with Ostertagia ostertagi in adult dairy cattle

Pitt, S.R.; M, Fox; Gerrelli, Dianne; Jacobs, D. Ε.

doi:10.1016/s0034-5288(18)30909-3

Cited by 17 publications

(7 citation statements)

References 6 publications

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“…These studies may not have made adequate allowance for differences in genotype, and the infected heifers may have had a better genetic potential for milk production than the uninfected controls (A. Kloosterman, unpublished observations). The report of one other study on the effect of experimental parasite infection on milk production did not indicate whether the non‐significant difference was positive or negative (Pitt and others 1988).…”

Section: Effects Of Gastrointestinal Parasites On Milk Productionmentioning

confidence: 96%

Anthelmintic treatment of dairy cows and its effect on milk production

Gross¹,

Ryan²,

Ploeger

1999

Veterinary Record

122

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The results of more than 80 experiments on gastrointestinal parasitism and the impact of anthelmintic treatment on milk production in dairy cattle were reviewed. Abattoir surveys of culled dairy cows, faecal egg counts in milking cows, and serological tests and worm counts in cull cows in milk production studies were collated to assess the level of parasitism in dairy herds. The studies were divided into four general categories: induced infections in previously uninfected cattle; naturally infected cattle treated in mid-lactation; naturally infected cattle treated one to three times during the dry period and/or just before or just after parturition; and naturally infected cattle treated repeatedly from early lactation or given strategic treatments throughout the year. In most studies, the milk production of anthelmintic-treated cattle was compared with that of untreated controls. The anthelmintics investigated included members of the organophosphate, benzimidazole, imidazothiazole and macrocyclic lactone groups. The number of experiments in which the medicated (or uninfected) group had a higher milk yield was compared with the number of experiments in which the control (or infected) group had a higher yield. Overall, the studies demonstrated that grazing dairy cattle are likely to be infected with gastrointestinal nematode parasites, usually Ostertagia ostertagi and Cooperia species. These infections may be present as inhibited larvae, and a periparturient or spring rise is associated with their emergence. There is, at present, no reliable means of determining whether a cow or a herd may be parasitised subclinically at a level sufficient to interfere with milk production. In 70 of 87 experiments (80 per cent) there was an increase in milk production (P < 0.001) after anthelmintic treatment, with a median increase of 0.63 kg/day. In each of the four trial categories, a majority of the studies showed that anthelmintic treatment increased milk production. The yield of milk fat by the medicated cows was greater than by the controls in 26 of the 35 experiments in which that variable was studied (P < 0.01).

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Section: Effects Of Gastrointestinal Parasites On Milk Productionmentioning

confidence: 96%

Anthelmintic treatment of dairy cows and its effect on milk production

Gross¹,

Ryan²,

Ploeger

1999

Veterinary Record

122

View full text Add to dashboard Cite

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“…The main advantage ofgastrin values over pepsinogen values seems to be that the former appear not to be influenced by hypersensitivity responses to incoming infective larvae (Armour et al, 1979;Wiggin and Gibbs, 1987;Pitt et al, 1988;Hilderson et al, 1989Hilderson et al, , 1991Hilderson et al, , 1992Xiao et al, 1991Xiao et al, , 1992. Particularly in Experiment 1, gastrin values decreased dramatically towards the end of the FGS, whereas the corresponding pepsinogen values remained elevated.…”

Section: Serum Pepsinogen and Gastrin Valuesmentioning

confidence: 99%

Quantitative estimation of the level of exposure to gastrointestinal nematode infection in first-year calves

Ploeger¹,

Kloosterman²,

Rietveld³

et al. 1994

Veterinary Parasitology

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“…It has activity on parietal cells, and its two major functions are stimulation of parietal cell multiplication and release of HCl. Changes in plasma gastrin concentration are associated with neoplastic and ulcerogenic gastric disease states (Smith et al, 1983) and have been studied in ruminants with parasitic diseases (Pitt et al, 1988). An increase in plasma gastrin may also help to sustain the rise in plasma pepsinogen levels in parasitized calves (Fox et al, 1989;Xiao et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Plasma Gastrin Activity and the Diagnosis of Bleeding Abomasal Ulcers in Cattle

Ok¹,

Şen

Turgut

et al. 2001

Journal of Veterinary Medicine Series A

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The present study was designed to evaluate the usefulness of plasma gastrin determinations as a diagnostic aid and to review the clinical and haematological findings in cattle with bleeding abomasal ulcers. Twenty-nine cows with bleeding abomasal ulcers and six healthy cows were used. Clinical and laboratory examinations, including plasma gastrin levels, were performed. Anorexia, depression, dark-coloured to black faeces, pale mucous membranes, abdominal pain, moderate tachycardia and tachypnoca were the most pronounced clinical symptoms in the cattle with bleeding abomasal ulcers. Plasma gastrin concentration was significantly higher (P < 0.05) in the cattle with bleeding abomasal ulcers than in healthy cows. The mean plasma gastrin concentration in healthy cattle was 103.2 pg/ml, while the mean plasma gastrin concentrations in cattle with bleeding abomasal ulcers were found to be 213.6 pg/ml. Haemoglobin levels, packed cell volume, total white blood cell count and mean corpuscular volume were significantly lower (P < 0.05) in the cows with bleeding abomasal ulcer than in the healthy cattle. The results of this study show that measurement of plasma gastrin can be useful in the diagnosis of bleeding abomasal ulcers in cattle.

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Blood gastrin and pepsinogen responses to subclinical infection with Ostertagia ostertagi in adult dairy cattle

Cited by 17 publications

References 6 publications

Anthelmintic treatment of dairy cows and its effect on milk production

Anthelmintic treatment of dairy cows and its effect on milk production

Quantitative estimation of the level of exposure to gastrointestinal nematode infection in first-year calves

Plasma Gastrin Activity and the Diagnosis of Bleeding Abomasal Ulcers in Cattle

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