Blood groups and malaria

Abstract

The possible relationship between erythrocyte antigens and the presence of malaria infection by P. vivax and P. falciparurn was sought in four different ethnic groups of two departments of Colombia. Malaria infection by P. falciparum was found in 91.4% of malaria infected blacks. No significant differences were found between the presence of malaria infection and ABO antigens. In the other blood groups, it was observed that groups MNSs conferred black people a greater Rr for malaria by both species of Plasmodium and that Duffy-negative blacks and indians appeared to be resistant to P. vivax infection. A predominance of P. vivax infection was observed in Katio indians while P.falciparum was predominant in Kuna indians; the reason for this finding still needs to be explored.

The association of genetic markers and malaria infection in the Brazilian Western Amazonian region

“…In spite of the fact that these phenomena might provoke an association of ABO blood groups and the number of malarial episodes, the results presented above do not enable to reject the null hypothesis that this polymorphic system is not associated with the number of malarial episodes. The absence of association between ABO system and malaria infection was also observed in other populations (Osisanyia 1983, Singh et al 1986, Bayoumi et al 1986, Montoya et al 1994 but Santos et al (1983) detected in Brazil a significant association between the presence of B antigen and the number of malarial episodes. Although our results pointed to the same direction, we were not able to confirm this observation by combining the frequency of B and AB individuals.…”

A cross sectional investigation of malaria epidemiology among seven tea estates in Assam, India

“…The ABO type blood groups have not been significantly contributing to the simple malaria infection, however these have been found associated with the rosette like formation in the blood cells (Facer and Brown 1979;Martin et al 1979;Montoya et al 1994). A protective effect of O blood group has been observed through the mechanism of reduced Plasmodium rosetting in Mali (Rowe et al 2007).…”

Genética epidemiológica de malária em Rondônia.

“…In spite of the fact that these phenomena might provoke an association of ABO blood groups and the number of malarial episodes, the results presented above do not enable to reject the null hypothesis that this polymorphic system is not associated with the number of malarial episodes. The absence of association between ABO system and malaria infection was also observed in other populations (Osisanyia 1983, Singh et al 1986, 1995, Bayoumi et al 1986, Montoya et al 1994 but Santos et al (1983) detected in Brazil a significant association between the presence of B antigen and the number of malarial episodes. Although our results pointed to the same direction, we were not able to confirm this observation by combining the frequency of B and AB individuals.…”