Blood Haematology, Serum Thyroid Hormones and Glutathione Peroxidase Status in Kacang Goats Fed Inorganic Iodine and Selenium Supplemented Diets

Abstract

The effects of dietary supplementation of selenium (Se), iodine (I), and a combination of both on the blood haematology, serum free thyroxine (FT4) and free triiodothyronine (FT3) hormones and glutathione peroxidase enzyme (GSH-Px) activity were examined on twenty four (7 to 8 months old, 22±1.17 kg live weight) Kacang crossbred male goats. Animals were randomly assigned to four dietary treatments (6 animals in each group). Throughout 100 d of feeding trial, the animals of control group (CON) received a basal diet, while the other three groups were offered basal diet supplemented with 0.6 mg/kg diet DM Se (SS), or 0.6 mg/kg diet DM I (PI), or a combination of both Se and I, each at 0.6 mg/kg diet DM (SSPI). The haematological attributes which are haemoglobin (Hb), red blood cell (RBC), packed cell volume (PCV), mean cell volume (MCV), white blood cells (WBC), band neutrophils (B Neut), segmented neutrophils (S Neut), lymphocytes (Lymph), monocytes (Mono), eosinophils (Eosin) and basophils (Baso) were similar among the four treatment groups, while serum levels of Se and I increased significantly (p<0.05) in the supplemented groups. The combined dietary supplementation of Se and I (SSPI) significantly increased serum FT3 in the supplemented animals. Serum GSH-Px activity increased significantly in the animals of SS and SSPI groups. It is concluded that the dietary supplementation of inorganic Se and I at a level of 0.6 mg/kg DM increased serum Se and I concentration, FT3 hormone and GSH-Px activity of Kacang crossbred male goats.

Effect Of Organic Selenium And Iodine Supplementation On Selenium And Thyroid Hormones Status Of Lactating Ewes And Lambs

“…An increased blood serum Se concentration in the ewes with high I and Se (HSeI) intake to the 60th day post partum shows the infl uence I on Se utilisation and is in accordance with Guyot et al [9] and Aghwan et al [21], who found a synergistic relationship between I and Se metabolism when both microelements were supplemented simultaneously. Higher I supplementation in HSeI group also led to a signifi cant (P< 0.01) increase of Se content in urine compared to the group HSe.…”

Effects of dietary supplementation of selenium and iodine on growth performance, carcass characteristics and histology of thyroid gland in goats

“…In the case of the I supplemented treatment (IP), the significant increase in ADG and total weight gain of the animals may be due to their higher thyroxine concentrations (Aghwan et al . ) which affected metabolic processes in the animals. The SSIP animals (combination of Se and I) showed a positive response in the growth performance in terms of total gain, daily gain and FCR.…”

The Impact of Dietary Supplementation of Iodine and Selenium on Nutrients Digetibility and Productive Performance of Ewes and Their Suckling Lambs

“…However, there was an interaction between I and Se to improve ADF digestibility (Qin et al, 2011). To the point, dietary combined supplementation of I plus Se (each at 0.6 mg/kg DM) markedly increased the concentrations of free T3 hormone, which is the biologically active form of thyroid hormones, compared to I or Se alone, suggesting possible synergistic effects of combined Se and I in improving metabolism (Aghwan et al, 2013).…”

“…It is well known that these hormones regulate energy metabolism, growth and development and thyroid activity, to synthesize its hormones, requires both I and Se. Pechova et al (2012) and Aghwan et al (2013) related the significant increase in ADG and total weight gain in goats fed supplemental I to their higher T 4 concentrations. At this point, it was noticed that maternal-supplemental I plus Se in pre-partum cows can improve their calves performance and immune status via improving the maternal mineral status (Gilles et al, 2009).…”