Blood Lead in End-Stage Renal Disease (ESRD) Patients who were on Maintainence Haemodialysis

M, Subha Palaneeswari; Rajan, P M Abraham Sam; Silambanan, Santhi; Jothimalar,

doi:10.7860/jcdr/2012/4865.2627

Cited by 13 publications

(11 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ESRD leads to accumulation of certain toxic elements, which affects normal functions of the body, and may have significant complications including cardiovascular disease, immune deficiency, anemia, renal function impairment, and bone disease. [ 85 ] Xerostomia was found in 28-59% of ESRD patients due to inability of kidneys to reabsorb sodium and the resultant polyuria. [ 86 87 ]…”

Section: Resultsmentioning

confidence: 99%

Xerostomia due to systemic disease: A review of 20 conditions and mechanisms

Mortazavi

Baharvand

Movahhedian

et al. 2014

Ann Med Health Sci Res

107

View full text Add to dashboard Cite

Xerostomia is a common complaint of nearly half of the elderly population and about one-fifth of younger adults. It causes several signs and symptoms, and compromise oral functions and health-related quality-of-life. Multiple reasons are proposed to describe the etiology of xerostomia such as local factors, psychogenic factors, and systemic diseases. In order to manage xerostomia effectively, identification of the main causality is mandatory. The aim of this review was to present systemic diseases leading to xerostomia with their mechanisms of action. We used various general search engines and specialized databases such as Google, Google Scholar, Yahoo, PubMed, PubMed Central, MedLine Plus, Medknow, EBSCO, ScienceDirect, Scopus, WebMD, EMBASE, and authorized textbooks to find relevant topics by means of Medical Subject Headings keywords such as “xerostomia,” “hyposalivations,” “mouth dryness,” “disease,” and “systemic.” We appraised 97 English-language articles published over the last 40 years in both medical and dental journals including reviews, meta-analysis, original papers, and case reports. Upon compilation of relevant data, it was concluded that autoimmune diseases most frequently involve salivary glands and cause xerostomia followed by diabetes mellitus, renal failure, and graft-versus-host disease. Moreover, the underlying mechanisms of systemic disease-related xerostomia are: autoimmunity, infiltration of immunocompetent cells, granuloma formation, fibrosis and dehydration, deposition of proteinaceous substances, bacterial infection, and side-effects of medications.

show abstract

Section: Resultsmentioning

confidence: 99%

Xerostomia due to systemic disease: A review of 20 conditions and mechanisms

Mortazavi

Baharvand

Movahhedian

et al. 2014

Ann Med Health Sci Res

107

View full text Add to dashboard Cite

show abstract

“…However, the mean lead level in hemodialysis patients was higher than the international standard level. Previous studies showed a higher lead level in hemodialysis patients than healthy people (15).…”

Section: Discussionmentioning

confidence: 89%

“…Palaneeswari et al studied 100 hemodialysis patients to measure the serum lead level and its relationship with hemodialysis duration. They found that serum lead level slightly increased with the increases in the duration of hemodialysis session (15).…”

Section: Discussionmentioning

confidence: 99%

“…The patients were divided into two groups, namely those with anemia (the case group) and those without anemia (the control group) based on their hemoglobin level (a participant with a hemoglobin level of less than 11.5 mg/dL was diagnosed with anemia) (14). The estimated sample size in each group was 35 according to the study by Palaneeswari et al (15).…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Correlation between blood lead level and anemia in hemodialysis patients

et al. 2020

View full text Add to dashboard Cite

Introduction: Studies show that blood lead level (BLL) is higher in hemodialysis patients than in healthy people. Lead can disrupt iron metabolism and hemoglobin synthesis and therefore it is regarded as a cause of anemia. Objectives: This study investigated the relationship between BLL and anemia in end-stage renal disease (ESRD) undergoing maintenance hemodialysis Patients and Methods: This case-control study was conducted on 70 patients who had received hemodialysis at least for three months. The participants were selected randomly among eligible patients considering the inclusion and exclusion criteria. Based on their hemoglobin levels, the participants were divided into two groups, namely patients with anemia (case) and those without anemia (control). Results: The mean age of the participants in the case and control groups were 63.8±11.02 and 55.4±13.34 years, respectively. There were significant differences between two groups regarding hemoglobin, C-reactive protein (CRP) and erythropoietin (EPo) levels (P < 0.05). There was a significant correlation between hemoglobin and ferritin levels in the case group and between the length of dialysis and serum iron level in the control group without anemia (P < 0.001). Conclusion: Our results showed no correlation between BLL and anemia, however the BLL was higher in those undergoing long-term maintenance hemodialysis. Our findings require further investigation with larger studies.

show abstract

“…ESRD represents a progressive clinical condition in which an irreversible loss of endogenous renal function below a sufficient degree is established, imposing permanent dependency on renal replacement therapy (RRT) to avoid life-threatening uremia and other complications. Treatment of this disease is affected through RRT, including peritoneal dialysis (PD), hemodialysis (HD), or kidney transplantation (KT) (9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

Quality of Life of Patients on Peritoneal Dialysis and Contributing Factors

Nili

Seirafian²,

Hosseini³

et al. 2023

jrenhep

View full text Add to dashboard Cite

In recent years, interest in Health-Related Quality of Life (HRQoL) as a major indicator of clinical efficacy and treatment outcome in patients of End-Stage Renal Disease (ESRD) has grown significantly. This study aimed to determine the contributing factors affecting the quality of life (QoL) of ESRD patients undergoing peritoneal dialysis (PD). A cross-sectional study was conducted on PD patients presented at PD centres of Al-Zahra and Noor hospitals in Isfahan, Iran, from May to August 2019. A total of 173 patients having peritoneal dialysis for more than 3 months filled the validated 36-item short-form health survey questionnaire (SF-36). Baseline demographic details and dialysis-related factors were collected from patients’ medical records. The overall QoL score of patients was 50.28 ± 20.87. Male patients had a higher QoL score than female patients (58.18 in males, compared to 48.18 in females; P = 0.04). A significant association between frequency of dialysis and quality of life was observed, where three sessions of dialysis per day yielded the highest quality of life (QoL score = 59.62; P = 0.047). A significant positive correlation was discovered between QoL score and residual renal function (P = 0.013). In addition, a higher QoL score was observed in self-employed patients (60.95), compared to housewives (46.49) (P = 0.001). QoL assessment should be included as an integral part of patient follow-up to evaluate treatment outcomes and implement possible interventions to improve patient’s quality of life.

show abstract

Blood Lead in End-Stage Renal Disease (ESRD) Patients who were on Maintainence Haemodialysis

Cited by 13 publications

References 16 publications

Xerostomia due to systemic disease: A review of 20 conditions and mechanisms

Xerostomia due to systemic disease: A review of 20 conditions and mechanisms

Correlation between blood lead level and anemia in hemodialysis patients

Quality of Life of Patients on Peritoneal Dialysis and Contributing Factors

Contact Info

Product

Resources

About