WHAT'S KNOWN ON THIS SUBJECT:The definition of hypertension in children is complex because of the age-, gender-, and heightspecific blood pressure algorithm. Blood pressure to height ratio was reported to easily identify hypertension in Chinese children living in a local area (Hebei Province).
WHAT THIS STUDY ADDS:Blood pressure to height ratio index is simple and accurate for screening for prehypertension and hypertension in Chinese children aged 6 to 17 years and can be used for early screening or treating Chinese children with hypertension.abstract OBJECTIVES: The definition of hypertension in children is too complex to be used by medical professionals and children and their parents because of the age-, gender-, and height-specific blood pressure (BP) algorithm. The aim of this study was to simplify the pediatric BP percentile references using BP to height ratio (BPHR, equal to BP/height) for screening for prehypertension and hypertension in Chinese children.METHODS: Data were obtained from the China Health and Nutrition Survey, which was conducted from 1991 to 2009 and included 11 661 children aged 6 to 17 years with complete data on age, gender, height, and BP values. Receiver operating characteristic curve analysis was performed to assess the performance of systolic BPHR (SBPHR) and diastolic BPHR (DBPHR) for screening for pediatric prehypertension and hypertension.
RESULTS:The optimal thresholds for defining prehypertension were 0.81 in children aged 6 to 11 years and 0.70 in adolescents aged 12 to 17 years for SBPHR and 0.52 in children and 0.46 in adolescents for DBPHR, respectively. The corresponding values for hypertension were 0.84, 0.78, 0.55, and 0.50, respectively. The negative predictive values were much higher (all $99%) for prehypertension and hypertension, although the positive predictive values were relatively lower, ranging from 13% to 75%.CONCLUSIONS: BPHR index is simple and accurate for screening for prehypertension and hypertension in Chinese children aged 6 to 17 years and can be used for early screening or treating Chinese children with hypertension. Pediatrics 2014;134:e106-e111 5 This report defined pediatric hypertension as systolic/diastolic blood pressure (SBP/DBP) above the 95th percentile specific to age, gender, and height. 5 These diagnostic criteria are widely used in epidemiologic surveys and clinical practice. In China, 2 diagnostic criteria for childhood hypertension have been established recently, which also used the similar BP algorithm. 6,7 This algorithm is too complex to be applied in clinical practice, and it is even more difficult for use by nonmedical professionals or children and their parents or guardians. In addition, hypertension in children is usually underdiagnosed in the outpatient clinics, mainly because of the complexity of the BP algorithm. 8 Therefore, a simple and accurate screening method to identify childhood hypertension is urgently needed. In 2011, Lu et al 9 first reported that BP to height ratio (BPHR) can easily and accurately identify hypertens...