Blood Volume in Congestive Heart Failure1

A Correlation of Clinical and Hemodynamic Studies in Patients With Hypothyroidism1

“…The arm to tongue circulation times in these patients were in the upper normal to slightly prolonged range (15 to 25 seconds) and blood volumes were normal to low in the five patients in whom this determination was made. These observations are consonant with the numerous data contained in other reports of patients with hypothyroidism (19,(40)(41)(42) and differ from the considerably prolonged circulation times and increased blood volumes commonly found in patients with chronic congestive heart failure (43,44). On the basis of the clinical evaluation of these patients it was felt, therefore, that in no instance could a definitive diagnosis of congestive heart failure be made.…”

RED CELL, PLASMA AND BLOOD VOLUME IN HEALTHY MEN MEASURED BY RADIOCHROMIUM (Cr51) CELL TAGGING AND HEMATOCRIT: INFLUENCE OF AGE, SOMATOTYPE AND HABITS OF PHYSICAL ACTIVITY ON THE VARIANCE AFTER REGRESSION OF VOLUMES TO HEIGHT AND WEIGHT COMBINED*

“…Our sample of adult males was of intermediate homogeneity, in that it included men from several racial origins whose ages extended to above 50 years and included physically active as well as sedentary persons, but only a few examples of extremely linear or obese body build. Most of the variation to be accounted for after consideration of height and weight is biologic rather than methodologic, as shown by our repeat studies and by similar experiences reported by workers using a variety of methods, for example, p32 (7,12,13), Cr5l (10), 1131 (15), and T-1824 (5,13,16 (14) found that consideration of fat thickness and girth in addition to height and weight lowered the coefficient of variation for Vwb from 9.6 to 7.6 per cent. Vwb, Vrbc and Vpl have been found to be directly related to body density (5,15), and Muldowney (17) found a surprisingly good correlation between Vrbc and lean body mass, considering that both were determined indirectly.…”

“…However, in comparison with the work which has been done with the dye (1)(2)(3)(4)(5) and carbon monoxide (6) methods, little attention has been given to the establishment of mean values for men and women or to study of the variance encountered among healthy subjects. Most clinical investigators have collected their own control data, based often on study of relatively few or not entirely healthy subjects (7)(8)(9)(10)(11)(12)(13).…”

Plasma and Blood Volume in an Æmia and the Effect of Transfusion

“…Commonly the volumes are expressed in relation to, and predicted from, the body weight. On this basis our figures for plasma volume (47 '76 millilitres per kilogram) are practically identical with those of Steinbeck (1950Steinbeck ( , 1954 for Australians, and are higher than the means of many other series which go even as low as 35 millilitres per kilogram (Berlin et alii, 1950;Gunton and Paul, 1955 (1955) and demonstrated in growing pigs by Bush et alii. It applies to the relation between volume and surface area as well as weight.…”