Blutzerfall, Galle und Urobilin

Brugsch, Theodor; Retzlaff, Karl

doi:10.1007/bf02622217

Cited by 28 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was not until Tarchanoff (2739), working 503 with bile fistula animals, demonstrated that the introduction of pure hemoglobin into the circulation led to increased excretion of bile pigment by the liver, that the ability of the animal body to convert hemoglobin into bilirubin became generally accepted. The latter has been confirmed by a number of workers (371,372,998,2605), and Whipple and his collaborators (cf. Section 8.1.)…”

Section: Breakdown Of Hemoglobin and Myohemoglobin To Dipyrrolic Compoundsmentioning

confidence: 70%

“…Almost all hypotheses ignored obvious physiological and histological hints as to the chain of reactions, and envisaged the transformation almost solely in terms of chemical steps which could be carried out at that time in the test tube. As a result of the isolation of hematin and hematoporphyrin the steps were considered to be hemoglobin, hematin, hematojlorphyrin, bilirubin (371,372,697,1859). While Brugsch's school (370-372) claimed that they had observed increases in bilirubin excretion after injection of hematin, and in this received some support from Van de Velde (286Jf) ,* these findings have not been confirmed by Gitter and Heilmeyer (1007) or by Duesberg (639).…”

Section: Earlier Theories Of the Mechanismmentioning

confidence: 99%

See 1 more Smart Citation

Hematin compounds and bile pigments; their constitution, metabolism, and function, by R. Lemberg and J.W. Legge.

Legge¹,

Lemberg²

1949

View full text Add to dashboard Cite

II. METHODS or INVESTIGATION* Only the naturally occurring hile pigments of type IXa are discussed.* .\11 tlie al).s()r[)ti()ii curves of the "hiliverdiiis" in Heihiieyers hook (121-i) are ohviously tliose of niixtiirt's of liiliverditi witli hiliruliiii (pages 1(51, 1()7) and other * The term K-urobilin is, however, used by the Fischer school to denote a mixture of side chain isomerides of mesobilene-(b) in contradistinction to mesobilene-(b) IXa.* It is not certain, however, whether the albumin is the only plasma protein able to combine with hematin (c/. Miller and Ailing, 191f9a).* Keilin and Smith {1502a) have been unable to confirm the results of Virtanen and Laine.XII. HEMOGLOBIN CATABOLISM, II * Cf., however, Bittner and Watson {28-3a). CHAPTER XIII FORMATION OF HEMOGLOBIN AND SYNTHESIS OF PORPHYRINSIN THE ANIMAL BODY * The hemoglobin found occasionally in some species of Daphnia (Fox,937aa) does not appear to have an essential physiologic function, although, like the hematin compounds mentioned above, it is passed on in parthenogenetic eggs. Even the chlorocruorin or erythrocruorin of serpulimorphid worms does not appear to be essential (Fox, 937a).Glaucobilin. See Mesobiliverdin. Globan, 211. See also Globin (denatured). Globin, denatured, 240, 258 combination with heme, 232 electrometric titration, 255 in erythrocytes, 525 isoelectric point, 255 renaturation, 259 Globin, native, 230, 258, 568 amino acids. See Hemoglobin. combination, with hematins, 239 with metalloporphyrins, 240 with porphyrins, 240 denaturation, 255 ff. 734 SUBJECT INDEX Globin native (contd.) electrometric titration, 255 differential of globin and hemiglobin, 244 fate in hemogIol>in breakdown, 548, 568 frictional ratio, 250 isoelectric point, 255 molecular weight, 250 oxidation, in autoxidation of hemoglobin, 390 in denaturation, 395, 478 preparation, 258 specificity, 321. See also Hemoglobin. synthesis in vivo, 610 Glutathione as anticatalase, 412 and choleglobin formation, 477, 478, 517 and dehydroascorbic acid, 470, 517, 518 in erythrocyte, 516, 522, 619 and hem/globin, 522 as substrate of cytochrome c, 376 Glycine, in porphyrin s\nthesis, 637 Gmelin reaction, 109, 112 (table), 116, 138 Green hemins, 201, 456, 490. See also Chlorophyll hemins, Pheophorbide kemin, Verdochemochrome.

show abstract

Section: Breakdown Of Hemoglobin and Myohemoglobin To Dipyrrolic Compoundsmentioning

confidence: 70%