Body composition assessment by bioelectrical impedance analysis among patients treated with L-dopa for Parkinson’s disease

Wilczyński, Jacek; Półrola, Paweł

doi:10.5114/ms.2018.76872

“…Contrary to the data above, some current study by Wilczyński and Półrola [27] did not confirm BC changes in PD subjects but demonstrated the sex features in fat mass (%), fat-free and muscle mass (kg), visceral fat, and other parameters of BC. Despite the fact that some studies confirmed the presence of sarcopenic obesity in PD subjects, some recent research studies demonstrated that appendicular lean body mass reliably correlated with cerebral cholinergic innervations in PD subjects independent of age [28].…”

Section: Discussioncontrasting

confidence: 99%

Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson’s Disease

Povoroznyuk

¹

,

Bystrytska

²

,

Grygorieva

³

et al. 2019

Parkinson's Disease

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Introduction. Current research studies demonstrate the changes of bone mineral density (BMD) in subjects with Parkinson’s disease (PD); however, data about bone quality and body composition (BC) indexes are insufficient. The aim of the study was to assess the parameters of BMD, ВС, and trabecular bone score (TBS) in PD males. Materials and Methods. We performed a cross-sectional case-control research design and examined 76 males aged 50–77 years old, who were divided into two groups: first group including men without PD n=38 and the second group including subjects with PD n=38. Disease duration was at least 5 years; all PD participants were at levodopa therapy. BMD of lumbar spine, femoral neck, total femur, radius, and total body and TBS Ll−L4 were measured using the DXA method. Whole-body DXA measures were also used for the study of total, lean, and fat masses, skeletal muscle index (SMI), appendicular lean mass index (ALMI), and fat mass index (FMI). Results. Our study showed an increased incidence of osteoporosis and significantly lower total body BMD (respectively, 1.20 ± 0.13 and 1.26 ± 0.10 g/cm2, p=0.05), but not lumbar spine and femoral neck BMDs, and higher TBS value in PD men comparing to the control group (respectively, 1.33 ± 0.12 and 1.22 ± 0.18 un., p=0.005). Also, we established significantly decreased lower extremities BMD indexes, but not upper extremities, spine, and trunk BMDs in PD males. The femoral neck, proximal femur, and lower extremities BMD indexes in PD men were reliably lower at the side of predominance of clinical symptoms. Parameters of appendicular lean mass and ALMI in PD males were reliably higher, but fat mass values and FMI were lower compared to the control group in the absence of significant differences in lean mass values and SMI in weight-matched control. Conclusion. Due to low BMD values, changes in BC are present in PD males, and appropriate screening and preventive strategies should be instigated to maintain bone health in PD subjects.

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“…In people with Parkinson's disease, falls occur more frequently in the general elderly population [ 1 ]. They are reported as experienced by 38-68%, constituting one of the most significant causes of morbidity and mortality [ 2 , 3 ]. Recurrent falls often cause traumatic consequences and shorten the duration of life in patients with PD by 7 years [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Risk Factors for Falls among Patients with Parkinson’s Disease

Wilczyński

¹

,

Ścipniak

²

,

Ścipniak

³

et al. 2021

BioMed Research International

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Introduction. The aim of this study was to assess the risk factors for falls in patients with Parkinson’s disease. Materials and Methods. The study comprised 53 participants (52.8% women and 47.2% men). The Hoehn and Yahr 5-point disability scale was used to assess the severity of Parkinson’s disease. The Tinetti Balance and Gait Scale were used to evaluate the risk of falls. The Katz scale was used to test the independence of people with PD. The Falls Efficacy Scale-International Short Form (FES-I) was implemented to assess fear of falling. Results. The majority of participants was at a high risk of falls, being at the same level for women and men. A significant relationship was noted between the risk of falls and subjective assessment of mobility ( χ 2 = 31.86 , p < 0.001 ), number of falls ( χ 2 = 37.92 , p < 0.001 ), independence of the subjects ( χ 2 = 19.28 , p < 0.001 ), type of injury suffered during the fall ( χ 2 = 36.93 , p < 0.001 ), external factors ( χ 2 = 33.36 , p < 0.001 ), and the level of fear of falling ( χ 2 = 8.88 , p < 0.001 ). A significant relationship also occurred between the number of falls and the fear of falling ( χ 2 = 33.49 , p < 0.001 ) and between the number of falls and disease severity ( χ 2 = 45.34 , p < 0.001 ). The applied physiotherapy did not reduce the risk of falls ( χ 2 = 3.18 , p = 0.17 ). Conclusions. Individuals who rated their mobility as good or excellent were at a low risk of falls. People who fell more times were at a high risk of falling. People more independent were at a low risk of falls. Previous injuries were the most associated with being at risk of falling. Uneven surfaces and obstacles on one’s path are the external factors most associated with the risk of falling. People with low levels of fall anxiety were at a low risk of falls. Most people with low fall anxiety have never fallen. Additionally, the majority of patients with stage 1 of the disease have not fallen at all. The reason for the ineffectiveness of physiotherapy may be due to the exercise programs used and the lack of systematic implementation of them. PD is different for each patient; thus, it is important to select individually customized physiotherapy depending on motor and nonmotor symptoms, as well as general health of a patient.

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“…We took into consideration 49 studies [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ] in which BMI was assessed, resulting in 5727 patients, 57.3% of whom were men and 40.9% of whom were women. The lowest reported mean BMI was 17.84 kg/m 2 [ ...…”

Section: Resultsmentioning

confidence: 99%

“…Many authors opted not to provide information on the exact number of patients at risk of malnutrition or malnourished, only the mean score of the questionnaire for the entire cohort studied [ 13 , 14 , 17 , 19 , 20 , 23 , 24 , 25 , 26 , 27 , 28 , 35 , 37 , 44 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Malnutrition in Patients with Parkinson’s Disease: A Systematic Review

Kacprzyk

¹

,

Milewska

²

,

Zarnowska

³

et al. 2022

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Objectives: This systematic review analyzed the prevalence of malnutrition in patients with Parkinson’s Disease. Study design: a systematic review. Method: Four databases—Cochrane, PubMed, Embase and Web of Science—were searched from October 2021 to June 2022 by two independent researchers. The inclusion criteria were as follows: patients above 18 years old with confirmed Parkinson’s Disease, performed screening nutritional assessment, cohort studies, case-control studies, and cross-sectional studies. Patients without Parkinson’s Disease and with other parkinsonian syndromes were excluded. Results: 49 studies were included in this systematic review. Patients ranged in age from 20 to 96 years. There were 5613 subjects included. According to Mini Nutritional Assessment, 23.9% (n = 634) participants were at risk of malnutrition and 11.1% (n = 294) were malnourished. According to BMI score, most patients were either obese or overweight. Conclusions: the prevalence of malnutrition or risk of malnutrition in the study group was significant. Therefore, more specific and detailed studies on the prevalence of malnutrition in patients with Parkinson’s Disease are needed.

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Body composition assessment by bioelectrical impedance analysis among patients treated with L-dopa for Parkinson’s disease

Cited by 4 publications

References 20 publications

Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson’s Disease

Bone Mineral Density, TBS, and Body Composition Indexes in Ukrainian Men with Parkinson’s Disease

Assessment of Risk Factors for Falls among Patients with Parkinson’s Disease

Prevalence of Malnutrition in Patients with Parkinson’s Disease: A Systematic Review

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