Body Size, Gender, and Transfusions as Determinants of Outcome After Coronary Operations

Risks Associated With the Transfusion of Various Blood Products in Aortic Valve Replacement

“…However, those that examined short-term outcome found a negative effect associated with plasma (13)(14)(15). Plasma transfusions have several well-documented adverse effects, such as allergic reactions, TRALI, and other immunological responses (16), which could explain the adverse shortterm outcome.…”

Indications for red blood cell transfusion in cardiac surgery: a systematic review and meta-analysis

“…These are based largely on the results of RCTs in non-cardiac surgery patients that indicate equivalence for restrictive transfusion thresholds [6][7][8] . They are also influenced by evidence from observational studies showing strong associations between the reversal of severe anaemia by RBC transfusion with adverse clinical outcomes, such as death, acute lung injury, acute kidney injury, stroke, myocardial infarction, sepsis, and surgical site infections [9][10][11] . RBC transfusion has important morbidity; haemolytic transfusion reactions and Transfusion Associated Lung Injury account for a significant number of deaths per year 12 but a causal relationship between RBC transfusion and the adverse outcomes suggested by observational analyses has yet to be established.…”

Allogeneic leukocytes in cardiac surgery: Good or bad?

“…It has been suggested that platelet transfusions in cardiac surgery might be associated with postoperative complications. Whether or not platelet and plasma transfusions contribute to such postoperative complications, or are just a surrogate marker for the need for a higher number of RBC transfusions Bilgin et [54]. Other studies that focused on plasma transfusions reported inconsistent findings [55,56].…”