Body temperatures during menopausal hot flashes

Abstract

Body temperatures during hot flashes were measured in a menopausal woman. Internal temperatures fell after each flash; lowest: rectal, 35.6 degrees C; vaginal, 35.6 degrees C; tympanic, 35.2 degrees C. Where sweating occurred, the skin temperature fell during the flash and rose after it. Finger and toe temperatures always showed a sharp rise at the onset of a flash with a slower fall after the flash. Only the cheeks showed additional temperature rises; maximum, 0.7 degrees C. The heart accelerated 13% at the onset of the flash but slowed immediately thereafter. The flash interval was sharply demarcated by undulations in the ECG baseline. There was never any premonitory sign of the imminence of a flash. A central excitatory state seemed to build up, perhaps by the accumulation of a chemical compound, but not of heat, which was explosively dischargedmthe thermal distress was probably evoked by vascular warming in the cheeks. Dabbing the malar prominences with cold water brought prompt relief.

Neuroendocrinology of Menopausal Flushes: An Hypothesis of Flush Mechanism

“…There was no Rush-associated change in blood pressure. We confirmed the finding of a rapid fluctuation of the electrocardiographic baseline during the subjective Rush episode, a finding which Molnar (1974) postulated was secondary to rapid changes in skin resistance caused by sweat duct opening and filling with perspiration. It has since been shown by Tataryn et al (1980) that skin conductance increases (or skin resistance decreases) significantly with the onset of the Rush and may be the most consistent objective parameter of the occurrence of a Rush.…”

“…In fact, it was not until 1974 that a systematic investigation of the physiological nature of menopausal flushes was undertaken (Molnar, 1974). Molnar carried out an elegant physiological study of hot flushes in a single subject and set the stage for a rapidly growing field of neuroendocrine research.…”

Mecanismo fisiopatológico de los sofocos-sudores inducidos por deprivación androgénica en el carcinoma prostático

“…Existe una vasodilatación periférica generalizada 11,12 que ocurre típicamente en los primeros segundos del inicio del cuadro 13 . Asimismo se incrementa la transpiración y la conductancia eléctrica, existiendo una gran correlación entre ambas mediciones 12 .…”

“…Asimismo se incrementa la transpiración y la conductancia eléctrica, existiendo una gran correlación entre ambas mediciones 12 . Se presenta un incremento de 2-mS durante 30 segundos en la conductancia cutánea durante la clínica de sofocos [14][15][16] .…”

Ορμονικοί Και Ανοσολογικοί Δείκτες Καταθλιπτικών Γυναικών Στην Κλιμακτήριο

“…Υψηλές περιβαλλοντικές θερµοκρασίες συνδέονται µε αυξηµενο αριθµό εξάψεων, ενώ το αντίθετο συµβαίνει µε χαµηλές θερµοκρασίες του περιβάλλοντος (142,143).…”