Bone and soft tissue non-Hodgkin lymphoma of the maxillofacial area: Report of two cases, literature review and new therapeutic strategies

Abstract

Primary mandibular non-Hodgkin lymphoma (NHL) and soft tissues NHL of the maxillofacial are extremely rare representing a minimal percentage of the head and neck tumors. Two cases of bone and soft tissue maxillofacial NHL are reported. Clinical, radiological and pathological features are described and the therapeutic procedures are discussed accordingly. Mandibular radiologic features have been carefully analyzed and discussed to achieve an early and accurate diagnosis avoiding improper dental therapies.

Platelet-rich fibrin (PRF) in implant dentistry in combination with new bone regenerative technique in elderly patients

“…It can be used solely or in combination with bone grafts, depending on the purpose [8] , [21] ; increases the healing rate of the grafted bone [8] , [23] ; it is an economical and quick option compared with recombinant growth factors when used in conjunction with bone grafts [24] …”

Radiographic Enlargement of Mandibular Canal as an Extranodal Primary Non-Hodgkin’s Lymphoma Early Sign in an Asymptomatic Patient

“…However, panoramic images are considered an important tool of investigation at early stage of malignancies like NHL, due to the fact that it allows the professionals to detect and visualize the first signs of the disease. CT may confirm these findings [5]. …”

“…When NHL affects oral cavity, around only 15% to 45% arise in maxilla or mandible [4]. The most usual sites are maxilla, mandible, palatal soft tissue, and gum, respectively [5]. Only 0.6% of all NHL are at mandible alone [5], and it may involve the inferior alveolar canal, frequently without any radiographic sign of bony changes [6].…”

Hemangiomas of the maxillofacial area: Case Report, Classification and Treatment Planning

“…In case of mixed lesions with different areas showing different vascular patterns, proper therapy will be adopted for each area. For skin areas involved in the vascular lesions, laser therapy or tissue expanders will be adopted in order to preserve as much as possible skin amount from ablative surgery [20]. Before surgery, detailed evaluation of lesion borders must be carried out by MRI total body and, in case of bone segments involvement, a CT Scan with contrast media will be carried out.…”